The case of dermatomyositis complicated with cecum perforation and panniculitis occured in a 62-year-old woman was reported. She was admitted to Keio University Hospital with a history of proximal muscular weakness, and dysphagia. Physical examination showed erythema over the face and shoulder. Serum level of muscle enzymes was remarkably increased. The diagnosis of dermatomyositis was made based on proximal muscular weakness, elevated serum level of muscle enzymes and myogenic change of electromyocar diogram. The treatment with 60mg/day of prednisolone was started, and was a good response. However, 7 months later the disease became active again when the amount of prednisolone was reduced to 13mg/day. Subsequently she complained of abdominal pain on the right lower quadrant. The surgical findings included peritonitis due to the perforation of the cecum and multiple ulcers of the cecum. After operation, azathioprine was added. Four years and g months later, she noticed skin erythema with ulceration and subcutaneous nodule. Skin biopsy indicated the findings of the panniculitis with membrano-cystic lesion.It was thought that both cecum perforation and panniculitis were caused by angiopathy which was often seen in childhood dermatomyositis.
|Number of pages||7|
|Journal||Japanese Journal of Clinical Immunology|
|Publication status||Published - 1997|
- Cecum perforation
ASJC Scopus subject areas
- Immunology and Allergy