An allylated firefly luciferin analogue with luciferase specific response in living cells

Yuma Ikeda, Tsuyoshi Saitoh, Kazuki Niwa, Takahiro Nakajima, Nobuo Kitada, Shojiro A. Maki, Moritoshi Sato, Daniel Citterio, Shigeru Nishiyama, Koji Suzuki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

An allylated firefly luciferin was successfully synthesized and its bioluminescence properties were evaluated. When applied to cellular imaging in combination with Eluc, which is one of the commercially available luciferases, this analogue displayed a luciferase-specific bioluminescence signal with prolonged emission (>100 min).

Original languageEnglish
Pages (from-to)1774-1777
Number of pages4
JournalChemical Communications
Volume54
Issue number14
DOIs
Publication statusPublished - 2018 Jan 1

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Firefly Luciferin
Bioluminescence
Luciferases
Cells
Imaging techniques

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Ikeda, Y., Saitoh, T., Niwa, K., Nakajima, T., Kitada, N., Maki, S. A., ... Suzuki, K. (2018). An allylated firefly luciferin analogue with luciferase specific response in living cells. Chemical Communications, 54(14), 1774-1777. https://doi.org/10.1039/c7cc09720d

An allylated firefly luciferin analogue with luciferase specific response in living cells. / Ikeda, Yuma; Saitoh, Tsuyoshi; Niwa, Kazuki; Nakajima, Takahiro; Kitada, Nobuo; Maki, Shojiro A.; Sato, Moritoshi; Citterio, Daniel; Nishiyama, Shigeru; Suzuki, Koji.

In: Chemical Communications, Vol. 54, No. 14, 01.01.2018, p. 1774-1777.

Research output: Contribution to journalArticle

Ikeda, Y, Saitoh, T, Niwa, K, Nakajima, T, Kitada, N, Maki, SA, Sato, M, Citterio, D, Nishiyama, S & Suzuki, K 2018, 'An allylated firefly luciferin analogue with luciferase specific response in living cells', Chemical Communications, vol. 54, no. 14, pp. 1774-1777. https://doi.org/10.1039/c7cc09720d
Ikeda, Yuma ; Saitoh, Tsuyoshi ; Niwa, Kazuki ; Nakajima, Takahiro ; Kitada, Nobuo ; Maki, Shojiro A. ; Sato, Moritoshi ; Citterio, Daniel ; Nishiyama, Shigeru ; Suzuki, Koji. / An allylated firefly luciferin analogue with luciferase specific response in living cells. In: Chemical Communications. 2018 ; Vol. 54, No. 14. pp. 1774-1777.
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