An analysis of factors related to the tail-like pattern of myxofibrosarcoma seen on MRI

Kazutaka Kikuta, Daisuke Kubota, Akihiko Yoshida, Hideo Morioka, Yoshiaki Toyama, Hirokazu Chuuman, Akira Kawai

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: Myxofibrosarcoma (MFS) is characterized by a high frequency of local recurrence after surgery because of infiltrative growth of the tumor cells. This infiltrative growth creates a characteristic ‘tail-like’ pattern on magnetic resonance imaging (MRI), and it has been reported that this pattern is especially obvious on gadolinium-enhanced MRI (Gd MRI). However, the relationship between the tail-like pattern seen on Gd MRI and clinicopathological features of MFS is still not clear. In this study, we performed a retrospective analysis to identify clinicopathological factors related to the tail-like pattern of the MRI findings in patients with MFS.

Materials and methods: We retrospectively analyzed 50 patients with MFS to identify factors related to the tail-like pattern.

Results: On Gd MRI, 32 of the 50 patients presented the tail-like pattern, whereas 18 presented a solid pattern. The clincopathological factors related to the tail-like pattern were evaluated by chi-squared test. A superficial origin (p = 0.0009) was most significantly related to the tail-like pattern. The 5-year recurrence-free survival (RFS) rate was 75.6 % for patients showing the tail-like pattern and 90.9 % for those showing the solid pattern. The corresponding 5-year disease-free survival (DFS) rates were 64.7 and 79.3 %, respectively. Thus in terms of both 5-year RFS and DFS, patients with the tail-like pattern tended to have a poorer outcome.

Conclusion: A superficial origin of MFS is significantly related to a tail-like pattern on Gd MRI. The tail-like pattern is associated with poorer prognosis. Further studies of tumor depth and the tail-like pattern on Gd MRI are needed.

Original languageEnglish
Pages (from-to)55-62
Number of pages8
JournalSkeletal Radiology
Volume44
Issue number1
DOIs
Publication statusPublished - 2014 Dec 4

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Gadolinium
Statistical Factor Analysis
Magnetic Resonance Imaging
Recurrence
Disease-Free Survival
Survival Rate
Growth
Neoplasms

Keywords

  • MRI
  • Myxofibrosarcoma
  • Tail like

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Kikuta, K., Kubota, D., Yoshida, A., Morioka, H., Toyama, Y., Chuuman, H., & Kawai, A. (2014). An analysis of factors related to the tail-like pattern of myxofibrosarcoma seen on MRI. Skeletal Radiology, 44(1), 55-62. https://doi.org/10.1007/s00256-014-1992-5

An analysis of factors related to the tail-like pattern of myxofibrosarcoma seen on MRI. / Kikuta, Kazutaka; Kubota, Daisuke; Yoshida, Akihiko; Morioka, Hideo; Toyama, Yoshiaki; Chuuman, Hirokazu; Kawai, Akira.

In: Skeletal Radiology, Vol. 44, No. 1, 04.12.2014, p. 55-62.

Research output: Contribution to journalArticle

Kikuta, K, Kubota, D, Yoshida, A, Morioka, H, Toyama, Y, Chuuman, H & Kawai, A 2014, 'An analysis of factors related to the tail-like pattern of myxofibrosarcoma seen on MRI', Skeletal Radiology, vol. 44, no. 1, pp. 55-62. https://doi.org/10.1007/s00256-014-1992-5
Kikuta, Kazutaka ; Kubota, Daisuke ; Yoshida, Akihiko ; Morioka, Hideo ; Toyama, Yoshiaki ; Chuuman, Hirokazu ; Kawai, Akira. / An analysis of factors related to the tail-like pattern of myxofibrosarcoma seen on MRI. In: Skeletal Radiology. 2014 ; Vol. 44, No. 1. pp. 55-62.
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