An anthraquinone - Enzyme - peptide hybrid as a photo-switchable enzyme

Shota Sotokawa, Takashi Kitamura, Daisuke Takahashi, Kazunobu Toshima

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Abstract

A purpose-designed anthraquinone-horseradish peroxidase (HRP)-cell penetrating peptide hybrid 1 showed high and effective cell permeability. Furthermore, 1 exhibited enzymatic activity without photo-irradiation, whereas significant self-degradation and loss of enzymatic activity occurred upon photo-irradiation in living cells.

Original languageEnglish
Pages (from-to)10614-10617
Number of pages4
JournalChemical Communications
Volume54
Issue number75
DOIs
Publication statusPublished - 2018 Jan 1

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ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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