An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus

Hideji Itokawa, Shunji Tsuruoka, Koichi Takeya, Noboru Mori, Toru Sonobe, Seiji Kosemura, Toshinori Hamanaka

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

An antitumor morphinane alkaloid named sinococuline was isolated from the MeOH extract of Cocculus trilobus. Its structure was determined by spectroscopic analysis.

Original languageEnglish
Pages (from-to)1660-1662
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume35
Issue number4
DOIs
Publication statusPublished - 1987
Externally publishedYes

Keywords

  • Cocculus trilobus
  • Menispermaceae
  • NMR spectrum
  • antitumor substance
  • morphinane alkaloid
  • sinococuline

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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  • Cite this

    Itokawa, H., Tsuruoka, S., Takeya, K., Mori, N., Sonobe, T., Kosemura, S., & Hamanaka, T. (1987). An Antitumor Morphinane Alkaloid, Sinococuline, from Cocculus trilobus. Chemical and Pharmaceutical Bulletin, 35(4), 1660-1662. https://doi.org/10.1248/cpb.35.1660