An overview of the total synthesis of africane-type sesquiterpenoids

Yutaka Matsuda, Yoko Saikawa, Masaya Nakata

Research output: Contribution to journalArticle

2 Citations (Scopus)


Africane-type sesquiterpenoids consist of a bicyclo[5.3.0]decane structure and have been isolated from various natural environments. Their characteristic C–C bond motifs, including a seven-membered ring core, fascinate many synthetic organic chemists. Thirteen total syntheses have been reported over the past four decades. The purpose of this digest is to provide an overview of these total syntheses of africane-type sesquiterpenoids, with an emphasis on methods for constructing the seven-membered ring structure.

Original languageEnglish
JournalTetrahedron Letters
Publication statusAccepted/In press - 2018 Jan 1


  • Africane
  • Medium-sized ring formation
  • Sesquiterpenoids
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'An overview of the total synthesis of africane-type sesquiterpenoids'. Together they form a unique fingerprint.

  • Cite this