An unusual sesquiterpene derivative from Ferula kuhistanica

Kimiko Tamemoto, Yoshihisa Takaishi, Kazuyoshi Kawazoe, Gisho Honda, Michiho Ito, Fumiyuki Kiuchi, Yoshio Takeda, Olimjon K. Kodzhimatov, Ozodbek Ashurmetov, Katsuhide Shimizu, Hideko Nagasawa, Yoshihiro Uto, Hitoshi Hori

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

An unusual new sesquiterpene derivative, kuhistaferone (1), was isolated from the fruits of the Uzbekistan medicinal plant Ferula kuhistanica. The structure of 1 was established on the basis of spectroscopic evidence. Compound 1 showed moderate cytotoxicity against the human colon tumor cell line HCT116.

Original languageEnglish
Pages (from-to)1323-1324
Number of pages2
JournalJournal of Natural Products
Volume65
Issue number9
DOIs
Publication statusPublished - 2002 Sep 1
Externally publishedYes

Fingerprint

Ferula
Uzbekistan
Sesquiterpenes
Cytotoxicity
Medicinal Plants
Fruits
Tumor Cell Line
sesquiterpenoids
colon
medicinal plants
cytotoxicity
Tumors
Fruit
Colon
Cells
cell lines
Derivatives
fruits
kuhistaferone
neoplasm cells

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Tamemoto, K., Takaishi, Y., Kawazoe, K., Honda, G., Ito, M., Kiuchi, F., ... Hori, H. (2002). An unusual sesquiterpene derivative from Ferula kuhistanica. Journal of Natural Products, 65(9), 1323-1324. https://doi.org/10.1021/np020020+

An unusual sesquiterpene derivative from Ferula kuhistanica. / Tamemoto, Kimiko; Takaishi, Yoshihisa; Kawazoe, Kazuyoshi; Honda, Gisho; Ito, Michiho; Kiuchi, Fumiyuki; Takeda, Yoshio; Kodzhimatov, Olimjon K.; Ashurmetov, Ozodbek; Shimizu, Katsuhide; Nagasawa, Hideko; Uto, Yoshihiro; Hori, Hitoshi.

In: Journal of Natural Products, Vol. 65, No. 9, 01.09.2002, p. 1323-1324.

Research output: Contribution to journalArticle

Tamemoto, K, Takaishi, Y, Kawazoe, K, Honda, G, Ito, M, Kiuchi, F, Takeda, Y, Kodzhimatov, OK, Ashurmetov, O, Shimizu, K, Nagasawa, H, Uto, Y & Hori, H 2002, 'An unusual sesquiterpene derivative from Ferula kuhistanica', Journal of Natural Products, vol. 65, no. 9, pp. 1323-1324. https://doi.org/10.1021/np020020+
Tamemoto K, Takaishi Y, Kawazoe K, Honda G, Ito M, Kiuchi F et al. An unusual sesquiterpene derivative from Ferula kuhistanica. Journal of Natural Products. 2002 Sep 1;65(9):1323-1324. https://doi.org/10.1021/np020020+
Tamemoto, Kimiko ; Takaishi, Yoshihisa ; Kawazoe, Kazuyoshi ; Honda, Gisho ; Ito, Michiho ; Kiuchi, Fumiyuki ; Takeda, Yoshio ; Kodzhimatov, Olimjon K. ; Ashurmetov, Ozodbek ; Shimizu, Katsuhide ; Nagasawa, Hideko ; Uto, Yoshihiro ; Hori, Hitoshi. / An unusual sesquiterpene derivative from Ferula kuhistanica. In: Journal of Natural Products. 2002 ; Vol. 65, No. 9. pp. 1323-1324.
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