Analysis of abnormal findings observed on brain MRI T 2 weighted image in a system for the detection of asymptomatic brain disease in 1,200 cases

Takashi Horiguchi, Kazunari Yoshida, Syuzo Sato, Masahiro Mizukami, Takeshi Kawase, Shigeo Toya

Research output: Contribution to journalArticle

2 Citations (Scopus)


In this study we described the significance of asymptomatic cerebral infarction (ACI) and periventricular hyperintensity (PVH) observed on brain MRI in a system for detection of asymptomatic brain disease with 1,200 cases. The risk factors (RF), population in each age bracket of ACt and PVH, among groups with hypertension (HTG) and without RF (no-RFG), were investigated. The RF of ACI were hypertension (HT), diabetes mellitus (DM), and aging. Without DM, those are common RF of PVH. The population of PVH and ACI with PVH increased with aging in no-RFG. On the other hand, only the population of ACI with PVH increased with aging in HTG. The rate of these abnormal findings in HTG was significantly higher than that in no-RFG. In addition, HT accelerated the occurence of these findings by 10-20 years. When patients were over 60 years old, ACI increased rapidly. Accordingly, we concluded that (1) PVH and ACI had a common background. (2) Long term follow up concerning the incidence of ACI in the group with only PVH was necessary. (3) It was desirable that treatment for RF should be effected before the age of sixty.

Original languageEnglish
Pages (from-to)821-826
Number of pages6
JournalBrain and Nerve
Issue number9
Publication statusPublished - 1998 Sep 1



  • Asymptomatic cerebral infarction
  • MRI
  • Periventricular hyperintensity

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this