Analysis of analgesic and antipyretic drugs by LC/MS

Tatsuo Shinozuka, Rika Nakajima, Osamu Ohue, Setsuko Takei, Tatsuya Murai, Masaru Terada

Research output: Contribution to journalArticle

Abstract

A procedure for simultaneous determination of sixteen analgesic and antipyretic drugs in human plasma has been developed using a liquid chromatography / mass spectrometry (LC/MS). The analgesic and antipyretic drugs in human plasma were extracted with a OASIS MAX® cartridge column. The detection limits were 0.1-3.0 μg/ml. The present procedure seems useful as a convenient screening and determination method in forensic chemistry.

Original languageEnglish
Pages (from-to)172-173
Number of pages2
JournalJapanese Journal of Forensic Toxicology
Volume19
Issue number2
Publication statusPublished - 2001

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Plasma (human)
Antipyretics
Liquid chromatography
Liquid Chromatography
Mass spectrometry
Analgesics
Mass Spectrometry
Pharmaceutical Preparations
Screening
Limit of Detection
poly(divinyl-co-N-vinylpyrrolidinone)

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Toxicology

Cite this

Shinozuka, T., Nakajima, R., Ohue, O., Takei, S., Murai, T., & Terada, M. (2001). Analysis of analgesic and antipyretic drugs by LC/MS. Japanese Journal of Forensic Toxicology, 19(2), 172-173.

Analysis of analgesic and antipyretic drugs by LC/MS. / Shinozuka, Tatsuo; Nakajima, Rika; Ohue, Osamu; Takei, Setsuko; Murai, Tatsuya; Terada, Masaru.

In: Japanese Journal of Forensic Toxicology, Vol. 19, No. 2, 2001, p. 172-173.

Research output: Contribution to journalArticle

Shinozuka, T, Nakajima, R, Ohue, O, Takei, S, Murai, T & Terada, M 2001, 'Analysis of analgesic and antipyretic drugs by LC/MS', Japanese Journal of Forensic Toxicology, vol. 19, no. 2, pp. 172-173.
Shinozuka T, Nakajima R, Ohue O, Takei S, Murai T, Terada M. Analysis of analgesic and antipyretic drugs by LC/MS. Japanese Journal of Forensic Toxicology. 2001;19(2):172-173.
Shinozuka, Tatsuo ; Nakajima, Rika ; Ohue, Osamu ; Takei, Setsuko ; Murai, Tatsuya ; Terada, Masaru. / Analysis of analgesic and antipyretic drugs by LC/MS. In: Japanese Journal of Forensic Toxicology. 2001 ; Vol. 19, No. 2. pp. 172-173.
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