Analysis of herbicides in water using temperature-responsive chromatography and an aqueous mobile phase

Eri Ayano, Yuji Okada, Chikako Sakamoto, Hideko Kanazawa, Teruo Okano, Masanori Ando, Tetsuji Nishimura

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

A simple and rapid method has been developed for herbicides in water using temperature-responsive liquid chromatography (LC) and a column packed with poly(N-isopropylacrylamide) (PNIPAAm), a polymer anchored on the stationary-phase surface of modified silica. PNIPAAm reversibly changes its hydrophilic/hydrophobic properties in water in response to temperature. The method was used to determine five sulfonylurea and three urea herbicides. Separation was achieved with a 10 mM ammonium acetate (pH 3.0) isocratic aqueous mobile phase, and by changing the column temperature. The analytes were extracted from water by off-line solid-phase extraction (SPE) with an N-vinyl-pyrrolidone polymer cartridge. The average recoveries of the eight herbicides from spiked pure water, tap water and river water were 70-130% with relative standard deviations (RSDs) of <10%. The limits of quantitation (LOQ) of the eight herbicides were between 1 and 4 μg l-1.

Original languageEnglish
Pages (from-to)281-285
Number of pages5
JournalJournal of Chromatography A
Volume1069
Issue number2
DOIs
Publication statusPublished - 2005 Apr 1

Keywords

  • LC
  • Poly(N-isopropylacrylamide)
  • Sulfonylurea herbicides
  • Temperature-responsive chromatography
  • Urea herbicides

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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