Analysis of metribuzin and its metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry

Shigemi Kai; Takeshi Akaboshi; Masumi Waki; Teruhisa Fuzimaki; Hideko Kanazawa

doi:10.3358/shokueishi.52.28

Analysis of metribuzin and its metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry

Shigemi Kai, Takeshi Akaboshi, Masumi Waki, Teruhisa Fuzimaki, Hideko Kanazawa

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

A method for simultaneous determination of metribuzin (MET) and three metribuzin metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed. MET and its metabolites were extracted from a sample with acetonitrile, followed by InertSepC18 and BondElut SAX cartridge cleanup. The LC separation was performed on a C18 column using 0.01 mol/L ammonium formate-acetonitrile-methanol (70 : 21 : 9) as the mobile phase and MS detection with both positive and negative ion electrospray ionization. The mean recoveries from 10 livestock products and seafoods were generally >60%, and the relative standard deviations were <20%.

Original language	English
Pages (from-to)	28-33
Number of pages	6
Journal	Journal of the Food Hygienic Society of Japan
Volume	52
Issue number	1
DOIs	https://doi.org/10.3358/shokueishi.52.28
Publication status	Published - 2011 Feb

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Keywords

Lc-MS/MS
Livestock product
Metribuzin
Metribuzin DA
Metribuzin DADK
Metribuzin DK
Seafood

ASJC Scopus subject areas

Food Science
Public Health, Environmental and Occupational Health

Cite this

Kai, S., Akaboshi, T., Waki, M., Fuzimaki, T., & Kanazawa, H. (2011). Analysis of metribuzin and its metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry. Journal of the Food Hygienic Society of Japan, 52(1), 28-33. https://doi.org/10.3358/shokueishi.52.28

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10.3358/shokueishi.52.28