Analysis of metribuzin and its metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry

Shigemi Kai; Takeshi Akaboshi; Masumi Waki; Teruhisa Fuzimaki; Hideko Kanazawa

doi:10.3358/shokueishi.52.28

Analysis of metribuzin and its metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry

Shigemi Kai, Takeshi Akaboshi, Masumi Waki, Teruhisa Fuzimaki, Hideko Kanazawa

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A method for simultaneous determination of metribuzin (MET) and three metribuzin metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed. MET and its metabolites were extracted from a sample with acetonitrile, followed by InertSepC18 and BondElut SAX cartridge cleanup. The LC separation was performed on a C18 column using 0.01 mol/L ammonium formate-acetonitrile-methanol (70 : 21 : 9) as the mobile phase and MS detection with both positive and negative ion electrospray ionization. The mean recoveries from 10 livestock products and seafoods were generally >60%, and the relative standard deviations were <20%.

Original language	English
Pages (from-to)	28-33
Number of pages	6
Journal	Journal of the Food Hygienic Society of Japan
Volume	52
Issue number	1
DOIs	https://doi.org/10.3358/shokueishi.52.28
Publication status	Published - 2011 Feb

Keywords

Lc-MS/MS
Livestock product
Metribuzin
Metribuzin DA
Metribuzin DADK
Metribuzin DK
Seafood

ASJC Scopus subject areas

Food Science
Public Health, Environmental and Occupational Health

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title = "Analysis of metribuzin and its metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry",

abstract = "A method for simultaneous determination of metribuzin (MET) and three metribuzin metabolites in livestock products and seafoods by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed. MET and its metabolites were extracted from a sample with acetonitrile, followed by InertSepC18 and BondElut SAX cartridge cleanup. The LC separation was performed on a C18 column using 0.01 mol/L ammonium formate-acetonitrile-methanol (70 : 21 : 9) as the mobile phase and MS detection with both positive and negative ion electrospray ionization. The mean recoveries from 10 livestock products and seafoods were generally >60%, and the relative standard deviations were <20%.",

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AU - Kanazawa, Hideko

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