Angioimmunoblastic T-cell lymphoma: A relatively common type of T-cell lymphoma in Sjörgen's syndrome

Masataka Saito, Tomoo Fukuda, Tetsuo Shiohara, Masafumi Homori

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13 Citations (Scopus)


An increased risk of developing lymphoma has been indicated in Sjögren's syndrome (SS), and the lymphomas in SS are usually B-cell type in origin. Interestingly, despite the rather low frequency of T-cell lymphoma in SS, angioimmunoblastic T-cell lymphoma (AILD) constitute the majority of T-cell lymphomas associated with SS. To the best of our knowledge, including our case, at least 11 out of 23 (48%) cases of T-cell lymphoma reported in association ith SS, were AILD. The fact that the development of B-cell lymphoma in SS is much more frequent than that of T-cell lymphoma, might be explained by differences in the situation between B and T cells, although the exact mechanism still remains uncertain.

Original languageEnglish
Pages (from-to)888-890
Number of pages3
JournalClinical and experimental rheumatology
Issue number6
Publication statusPublished - 2005 Nov 1



  • Angioimmunoblastic T-cell lymphoma
  • Sjögren's syndrome

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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