Anterior mediastinal lymphoma arising after resection of an invasive thymoma and immunosuppressive therapy for complicated myasthenia gravis

Kohei Hashimoto, Hirohisa Horinouchi, Takashi Ohtsuka, Mitsutomo Kohno, Yotaro Izumi, Yuichiro Hayashi, Hiroaki Nomori

Research output: Contribution to journalArticle

1 Citation (Scopus)


We present the case of a 56-year-old woman with an anterior mediastinal tumor who has past history of myasthenia gravis and invasive thymoma. Furthermore, she had superior vena cava syndrome that was caused by a rapidly growing tumor. A biopsy proved diffuse large B-cell lymphoma. After 8 courses of chemotherapy, remission of the lymphoma was achieved. Because a second primary malignancy, including lymphoma, can occur in patients with thymoma, a biopsy is necessary for tumors located in the anterior mediastinum, particularly in patients with a history of treatment for thymoma, to distinguish between recurrence and a second primary malignancy.

Original languageEnglish
Pages (from-to)485-488
Number of pages4
JournalAnnals of Thoracic and Cardiovascular Surgery
Issue number6
Publication statusPublished - 2013 Dec 30



  • Mediastinal tumor
  • Second malignancy
  • Thymoma

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Gastroenterology

Cite this