Anterior mediastinal lymphoma arising after resection of an invasive thymoma and immunosuppressive therapy for complicated myasthenia gravis

Kohei Hashimoto, Hirohisa Horinouchi, Takashi Ohtsuka, Mitsutomo Kohno, Yotaro Izumi, Yuichiro Hayashi, Hiroaki Nomori

Research output: Contribution to journalArticle

Abstract

We present the case of a 56-year-old woman with an anterior mediastinal tumor who has past history of myasthenia gravis and invasive thymoma. Furthermore, she had superior vena cava syndrome that was caused by a rapidly growing tumor. A biopsy proved diffuse large B-cell lymphoma. After 8 courses of chemotherapy, remission of the lymphoma was achieved. Because a second primary malignancy, including lymphoma, can occur in patients with thymoma, a biopsy is necessary for tumors located in the anterior mediastinum, particularly in patients with a history of treatment for thymoma, to distinguish between recurrence and a second primary malignancy.

Original languageEnglish
Pages (from-to)485-488
Number of pages4
JournalAnnals of Thoracic and Cardiovascular Surgery
Volume19
Issue number6
DOIs
Publication statusPublished - 2013

Fingerprint

Thymoma
Myasthenia Gravis
Immunosuppressive Agents
Lymphoma
Second Primary Neoplasms
Superior Vena Cava Syndrome
Biopsy
Neoplasms
Lymphoma, Large B-Cell, Diffuse
Mediastinum
Therapeutics
Recurrence
Drug Therapy

Keywords

  • Mediastinal tumor
  • Second malignancy
  • Thymoma

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Gastroenterology

Cite this

Anterior mediastinal lymphoma arising after resection of an invasive thymoma and immunosuppressive therapy for complicated myasthenia gravis. / Hashimoto, Kohei; Horinouchi, Hirohisa; Ohtsuka, Takashi; Kohno, Mitsutomo; Izumi, Yotaro; Hayashi, Yuichiro; Nomori, Hiroaki.

In: Annals of Thoracic and Cardiovascular Surgery, Vol. 19, No. 6, 2013, p. 485-488.

Research output: Contribution to journalArticle

Hashimoto, Kohei ; Horinouchi, Hirohisa ; Ohtsuka, Takashi ; Kohno, Mitsutomo ; Izumi, Yotaro ; Hayashi, Yuichiro ; Nomori, Hiroaki. / Anterior mediastinal lymphoma arising after resection of an invasive thymoma and immunosuppressive therapy for complicated myasthenia gravis. In: Annals of Thoracic and Cardiovascular Surgery. 2013 ; Vol. 19, No. 6. pp. 485-488.
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