Antibacterial and antiproliferative activity of cationic fullerene derivatives

Tadahiko Mashino, Dai Nishikawa, Kyoko Takahashi, Noriko Usui, Takao Yamori, Masako Seki, Toyoshige Endo, Masataka Mochizuki

Research output: Contribution to journalArticle

114 Citations (Scopus)

Abstract

We examined the antibacterial and antiproliferative activities of alkylated C60-bis(N,N-dimethylpyrrolidinium iodide) derivatives. The fullerene derivatives inhibited bacteria and cancer cell growth effectively. However, the fullerene derivatives with a long alkyl chain did not show antibacterial activity.

Original languageEnglish
Pages (from-to)4395-4397
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume13
Issue number24
DOIs
Publication statusPublished - 2003 Dec 15

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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