Antineutrophil cytoplasmic antibody-associated vasculitis involving diffuse alveolar hemorrhage, rapidly progressive glomerulonephritis and hypereosinophilia

Hirofumi Kamata, Hidefumi Koh, Yasuhiro Okubo, Hiroyoshi Kunimoto, Atsushi Chiyotani, Koichi Sayama, Naoki Hasegawa, Makio Mukai

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The classification of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has limitations because the condition includes disorders with similar general clinical features, similar characteristics of lung and renal involvement and a positive ANCA serology. A 40-year-old woman was admitted to our hospital for hemoptysis and dyspnea. She had no history of bronchial asthma. Laboratory examinations revealed hypereosinophilia, positive anti-myeloperoxidase antibodies, hematuria and proteinuria. The patient was ultimately diagnosed with AAV associated with diffuse alveolar hemorrhage, rapidly progressive glomeru-lonephritis and hypereosinophilia without bronchial asthma. Obtaining a definitive diagnosis of ANCA vascu-litis can be very difficult, and the characteristics of this case were not compatible with the findings of typical AVV. We herein report a rare case of AVV.

Original languageEnglish
Pages (from-to)2253-2257
Number of pages5
JournalInternal Medicine
Volume52
Issue number19
DOIs
Publication statusPublished - 2013 Oct 8

Keywords

  • ANCA-associated vasculitis
  • Diffuse alveolar hemorrhage
  • Hypereosinophilia
  • Rapidly progressive glomerulonephritis

ASJC Scopus subject areas

  • Internal Medicine

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