TY - GEN
T1 - Antithrombogenicity of nano porous polyethersulfone membrane coated with fluorinated diamond-like carbon
AU - Sanada, I.
AU - Ito, H.
AU - Prihandana, G. S.
AU - Noborisaka, M.
AU - Miki, N.
AU - Suzuki, T.
AU - Kanno, Y.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - We have ever developed micro dialysis system that consists of micro channels and polyethersulfone (PES) membranes. However, when blood was used in dialysis experiments, platelets adhered to the surface of membrane and performance of the membrane degraded. Therefore, we modify the surface of PES membranes by coating fluorinated diamond-like carbon (F-DLC). We examined antithrombogencity of the F-DLC/PES membranes using a microfluidic device and experimentally found that F-DLC drastically reduced the amount of cells attached to the surface. We conducted long-term experiments for 1 week and the diffusion characteristics were found to retrogress because of fouling without the surface modification.
AB - We have ever developed micro dialysis system that consists of micro channels and polyethersulfone (PES) membranes. However, when blood was used in dialysis experiments, platelets adhered to the surface of membrane and performance of the membrane degraded. Therefore, we modify the surface of PES membranes by coating fluorinated diamond-like carbon (F-DLC). We examined antithrombogencity of the F-DLC/PES membranes using a microfluidic device and experimentally found that F-DLC drastically reduced the amount of cells attached to the surface. We conducted long-term experiments for 1 week and the diffusion characteristics were found to retrogress because of fouling without the surface modification.
KW - Dialysis system
KW - Fluorinated diamond-like carbon
KW - Nano porous polyethersulfone membrane
UR - http://www.scopus.com/inward/record.url?scp=84907331946&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907331946&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84907331946
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 808
EP - 810
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Y2 - 27 October 2013 through 31 October 2013
ER -