Antitumor effect of chemically synthesized (+)-goniopypyrone

T. K.M. Shing, M. Look, Y. M. Choy

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Chemically synthesized (+)-goniopypyrone was found to suppress the growth of cultured Ehrlich ascites tumor cells as well as PU5-1.8 cells. The ED50 values were found to be 35 and 30 μg/ml for the two cell lines used. An LD50 of 193 μg/ml was observed in the brine shrimp bioassay.

Original languageEnglish
Pages (from-to)132-134
Number of pages3
JournalCHEMOTHERAPY
Volume39
Issue number2
DOIs
Publication statusPublished - 1993 Jan 1

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Keywords

  • (+)-epi-goniotriol
  • (+)-goniopypyrone
  • Ehrlich ascites tumor
  • PU5-1.8

ASJC Scopus subject areas

  • Oncology
  • Pharmacology
  • Drug Discovery
  • Pharmacology (medical)
  • Infectious Diseases

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