TY - GEN
T1 - Application of carbon monoxide (CO) laser for laser balloon angioplasty
AU - Miyamoto, Akira
AU - Sakurada, Masami
AU - Mizuno, Kyoichi
AU - Kurita, Akira
AU - Nakamura, Haruo
AU - Suda, Akira
AU - Arai, Tsunenori
AU - Kikuchi, Maloto
PY - 1990
Y1 - 1990
N2 - CO laser may be efficient for thermal fusion of intima of arterial wall without adventitial tissue damage because of high tissue absorption. To investigate the efficacy of CO laser as a laser beam for laser balloon angioplasty (LBA). CO laser was irradiated to aortic tissue through 30μm polyethylene membrane and tissue temperature was measured by a thermistor. At 20watt/cm2 200joules/cm2 continuous laser exposure (CE), tissue temperature was above 100°C within a depth of 1mm and rapidly decreased to 60°C or below between 2 and 3mm in depth. Moreover, adventitial temperature could be decreased by changing duty ratio (exposure duration/interval) of intermittent laser exposure (IE) despite of the same laser energy. Light microscopy showed high degree of medial coagulation necrosis in CE, however thermal coagulation was observed only at the surface of intima of aortic tissue in IE at duty ration 1/2. These findings suggested CO laser could coagulate intimal layer with less deep thermal damage compared to Nd-YAG laser and that IE was better for superficial welding than CE at the same energy. We concluded that CO laser might be more efficient as a laser beam for LBA than Nd-YAG laser.
AB - CO laser may be efficient for thermal fusion of intima of arterial wall without adventitial tissue damage because of high tissue absorption. To investigate the efficacy of CO laser as a laser beam for laser balloon angioplasty (LBA). CO laser was irradiated to aortic tissue through 30μm polyethylene membrane and tissue temperature was measured by a thermistor. At 20watt/cm2 200joules/cm2 continuous laser exposure (CE), tissue temperature was above 100°C within a depth of 1mm and rapidly decreased to 60°C or below between 2 and 3mm in depth. Moreover, adventitial temperature could be decreased by changing duty ratio (exposure duration/interval) of intermittent laser exposure (IE) despite of the same laser energy. Light microscopy showed high degree of medial coagulation necrosis in CE, however thermal coagulation was observed only at the surface of intima of aortic tissue in IE at duty ration 1/2. These findings suggested CO laser could coagulate intimal layer with less deep thermal damage compared to Nd-YAG laser and that IE was better for superficial welding than CE at the same energy. We concluded that CO laser might be more efficient as a laser beam for LBA than Nd-YAG laser.
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M3 - Conference contribution
AN - SCOPUS:0025530829
SN - 0819402427
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 95
EP - 98
BT - Proceedings of SPIE - The International Society for Optical Engineering
A2 - Katzir, Abraham
PB - Publ by Int Soc for Optical Engineering
T2 - Proceedings of Optical Fibers in Medicine V
Y2 - 14 January 1990 through 19 January 1990
ER -