Application of FITC-labeled ternatin on its cellular localization in 3T3-L1 murine preadipocytes

Kenichiro Shimokawa, Osamu Ohno, Kaoru Yamada, Yuichi Oba, Daisuke Uemura

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Abstract

The cellular localization of a potent fat-accumulation inhibitor (-)-ternatin was investigated. FITC-labeled ternatin, a chemical probe for current study, was synthesized from a highly bioactive ternatin analogue using Click Chemistry, which was found to be bioactive. The treatment of 3T3-L1 murine preadipocytes with synthetic probe revealed that (-)-ternatin is localized in a specific organelle of 3T3-L1 cells.

Original languageEnglish
Pages (from-to)150-151
Number of pages2
JournalChemistry Letters
Volume38
Issue number2
DOIs
Publication statusPublished - 2009 Jul 20

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ASJC Scopus subject areas

  • Chemistry(all)

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