Application of high pressure induced by water-freezing to the direct catalytic asymmetric three-component List-Barbas-Mannich reaction

Yujiro Hayashi, Wataru Tsuboi, Mitsuru Shoji, Noriyuki Suzuki

Research output: Contribution to journalArticle

132 Citations (Scopus)

Abstract

High pressure induced by water-freezing has been successfully applied to the direct catalytic asymmetric-three component List-Barbas-Mannich reaction, in which higher yield and better enantioselectivity can be realized than those from the reaction at room temperature under 0.1 MPa.

Original languageEnglish
Pages (from-to)11208-11209
Number of pages2
JournalJournal of the American Chemical Society
Volume125
Issue number37
DOIs
Publication statusPublished - 2003 Sep 17

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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