Assessment of bone quality. Bone remodeling and bone quality

Gen ichiro Sano, Koichi Matsuo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Bone remodeling is a sequential process consisting of osteoclastic bone resorption and osteoblastic bone formation. Excess bone remodeling reduces bone mass, while suppressed bone remodeling increases it. Bisphosphonate treatment increases bone mass in patients with osteoporosis. However, bone strength is determined not only by mass but also by bone quality, and suppressed bone remodeling may reduce bone quality due to accumulation of micro fractures and to other mechanisms. Therefore understanding the relationship between bone remodeling and bone quality is essential to design interventions to effectively treat osteoporosis.

Original languageEnglish
Pages (from-to)315-320
Number of pages6
JournalClinical calcium
Volume18
Issue number3
Publication statusPublished - 2008 Mar

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Bone Remodeling
Bone and Bones
Osteoporosis
Stress Fractures
Diphosphonates
Bone Resorption
Osteogenesis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Assessment of bone quality. Bone remodeling and bone quality. / Sano, Gen ichiro; Matsuo, Koichi.

In: Clinical calcium, Vol. 18, No. 3, 03.2008, p. 315-320.

Research output: Contribution to journalArticle

Sano, Gen ichiro ; Matsuo, Koichi. / Assessment of bone quality. Bone remodeling and bone quality. In: Clinical calcium. 2008 ; Vol. 18, No. 3. pp. 315-320.
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