Abstract
Background: Cardiovascular diseases and/or risk factors (CVDRF) have been reported as risk factors for severe coronavirus disease 2019 (COVID-19). Methods and Results: In total, we selected 693 patients with CVDRF from the CLAVIS-COVID database of 1,518 cases in Japan. The mean age was 68 years (35% females). Statin use was reported by 31% patients at admission. Statin users exhibited lower incidence of extracorporeal membrane oxygenation (ECMO) insertion (1.4% vs. 4.6%, odds ratio [OR]: 0.295, P=0.037) and septic shock (1.4% vs. 6.5%, OR: 0.205, P=0.004) despite having more comorbidities such as diabetes mellitus. Conclusions: This study suggests the potential benefits of statins use against COVID-19.
Original language | English |
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Pages (from-to) | 939-943 |
Number of pages | 5 |
Journal | Circulation Journal |
Volume | 85 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2021 |
Keywords
- Cardiovascular risk factors
- Coronavirus disease 2019 (COVID-19)
- Statin
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine