Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women: The Ohasama study

Mami Seki, Ryusuke Inoue, Takayoshi Ohkubo, Masahiro Kikuya, Azusa Hara, Hirohito Metoki, Takuo Hirose, Megumi Tsubota-Utsugi, Kei Asayama, Atsuhiro Kanno, Taku Obara, Haruhisa Hoshi, Kazuhito Totsune, Hiroshi Satoh, Yutaka Imai

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Objective: Only a few of numerous epidemiological studies have demonstrated a positive association between environmental tobacco smoke (ETS) exposure and blood pressure (BP), despite experimental studies showing such a positive association. The association between home blood pressure (HBP) and ETS exposure was investigated in the general population. Methods: Five hundred and seventy-nine nonsmoking Japanese women were enrolled. The participants were classified into four categories according to their responses to a self-administered questionnaire: unexposed women (non-ETS), women exposed at home [ETS(home)], at the workplace/other places [ETS(work/other)] and at home and at the workplace/other places [ETS(both)]. Variables were compared using analysis of covariance adjusted for age, marital status, body mass index, diabetes mellitus, stroke, heart disease, hyperlipidemia, alcohol intake, salt intake and activity levels. Results: In participants without antihypertensive medication, systolic morning HBP in ETS(both) was 4 mmHg higher than that in non-ETS (116.8 ± 1.01 vs. 113.1 ± 1.08 mmHg, P = 0.02) and systolic morning HBP in ETS(home) and systolic evening HBP in ETS(both) were 3 mmHg higher than those in non-ETS (116.2 ± 1.07 vs. 113.1 ± 1.08 mmHg, P = 0.04; and 115.3 ± 1.02 vs. 111.9 ± 1.09 mmHg, P = 0.03, respectively). In participants with antihypertensive medication, ETS exposure status was not significantly associated with increased HBP levels. Conclusions: A positive association between HBP levels and ETS exposure was confirmed. HBP measurement is recommended in population-based studies investigating the effects of ETS exposure. ETS exposure may increase BP, thereby synergistically contributing to unfavorable cardiovascular outcomes along with other deleterious effects of ETS.

Original languageEnglish
Pages (from-to)1814-1820
Number of pages7
JournalJournal of hypertension
Volume28
Issue number9
DOIs
Publication statusPublished - 2010 Sep 1
Externally publishedYes

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Smoke
Tobacco
Blood Pressure
Workplace
Antihypertensive Agents
Marital Status
Hyperlipidemias
Population
Epidemiologic Studies
Heart Diseases
Diabetes Mellitus
Body Mass Index

Keywords

  • blood pressure
  • blood pressure monitoring ambulatory
  • cardiovascular diseases
  • home blood pressure monitoring
  • particulate matter
  • passive smoking

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women : The Ohasama study. / Seki, Mami; Inoue, Ryusuke; Ohkubo, Takayoshi; Kikuya, Masahiro; Hara, Azusa; Metoki, Hirohito; Hirose, Takuo; Tsubota-Utsugi, Megumi; Asayama, Kei; Kanno, Atsuhiro; Obara, Taku; Hoshi, Haruhisa; Totsune, Kazuhito; Satoh, Hiroshi; Imai, Yutaka.

In: Journal of hypertension, Vol. 28, No. 9, 01.09.2010, p. 1814-1820.

Research output: Contribution to journalArticle

Seki, M, Inoue, R, Ohkubo, T, Kikuya, M, Hara, A, Metoki, H, Hirose, T, Tsubota-Utsugi, M, Asayama, K, Kanno, A, Obara, T, Hoshi, H, Totsune, K, Satoh, H & Imai, Y 2010, 'Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women: The Ohasama study', Journal of hypertension, vol. 28, no. 9, pp. 1814-1820. https://doi.org/10.1097/HJH.0b013e32833a3911
Seki, Mami ; Inoue, Ryusuke ; Ohkubo, Takayoshi ; Kikuya, Masahiro ; Hara, Azusa ; Metoki, Hirohito ; Hirose, Takuo ; Tsubota-Utsugi, Megumi ; Asayama, Kei ; Kanno, Atsuhiro ; Obara, Taku ; Hoshi, Haruhisa ; Totsune, Kazuhito ; Satoh, Hiroshi ; Imai, Yutaka. / Association of environmental tobacco smoke exposure with elevated home blood pressure in Japanese women : The Ohasama study. In: Journal of hypertension. 2010 ; Vol. 28, No. 9. pp. 1814-1820.
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AU - Seki, Mami

AU - Inoue, Ryusuke

AU - Ohkubo, Takayoshi

AU - Kikuya, Masahiro

AU - Hara, Azusa

AU - Metoki, Hirohito

AU - Hirose, Takuo

AU - Tsubota-Utsugi, Megumi

AU - Asayama, Kei

AU - Kanno, Atsuhiro

AU - Obara, Taku

AU - Hoshi, Haruhisa

AU - Totsune, Kazuhito

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N2 - Objective: Only a few of numerous epidemiological studies have demonstrated a positive association between environmental tobacco smoke (ETS) exposure and blood pressure (BP), despite experimental studies showing such a positive association. The association between home blood pressure (HBP) and ETS exposure was investigated in the general population. Methods: Five hundred and seventy-nine nonsmoking Japanese women were enrolled. The participants were classified into four categories according to their responses to a self-administered questionnaire: unexposed women (non-ETS), women exposed at home [ETS(home)], at the workplace/other places [ETS(work/other)] and at home and at the workplace/other places [ETS(both)]. Variables were compared using analysis of covariance adjusted for age, marital status, body mass index, diabetes mellitus, stroke, heart disease, hyperlipidemia, alcohol intake, salt intake and activity levels. Results: In participants without antihypertensive medication, systolic morning HBP in ETS(both) was 4 mmHg higher than that in non-ETS (116.8 ± 1.01 vs. 113.1 ± 1.08 mmHg, P = 0.02) and systolic morning HBP in ETS(home) and systolic evening HBP in ETS(both) were 3 mmHg higher than those in non-ETS (116.2 ± 1.07 vs. 113.1 ± 1.08 mmHg, P = 0.04; and 115.3 ± 1.02 vs. 111.9 ± 1.09 mmHg, P = 0.03, respectively). In participants with antihypertensive medication, ETS exposure status was not significantly associated with increased HBP levels. Conclusions: A positive association between HBP levels and ETS exposure was confirmed. HBP measurement is recommended in population-based studies investigating the effects of ETS exposure. ETS exposure may increase BP, thereby synergistically contributing to unfavorable cardiovascular outcomes along with other deleterious effects of ETS.

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