Association of short sleep duration with impaired glucose tolerance or diabetes mellitus

Sayuri Katano, Yasuyuki Nakamura, Aki Nakamura, Yoshitaka Murakami, Taichiro Tanaka, Toru Takebayashi, Akira Okayama, Katsuyuki Miura, Tomonori Okamura, Hirotsugu Ueshima

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Aims/Introduction: To examine the cross-sectional relationship between sleep duration and impaired glucose tolerance (IGT), including diabetes mellitus (DM), we analyzed a large-scale healthy workers database in Japan. Materials and Methods: We examined the baseline database of 4143 participants (3415 men and 728 women) aged 19-69years. Sleep duration of participants was categorized into four groups: <6, 6 to <7, 7 to <8 and ≥8h. The physical activity of each participant was classified according to the International Physical Activity Questionnaire (IPAQ). We defined IGT including DM (IGT/DM) in the present study according to previous studies as follows: fasting blood sugar level ≥110mg/dL, or if <8h after meals ≥140mg/dL, or on medication for diabetes mellitus, or those diagnosed as having DM. Logistic regression was applied to estimate the odds ratio (OR) to examine the relationship between IGT/DM, sleep duration and other related factors. Results: The number of participants with IGT/DM was 402 (9.7%). The factors that significantly associated with IGT/DM were age (OR 1.08, 95% confidence interval [CI] 1.07-1.10, P<0.001), high blood pressure (OR 1.94, CI 1.52-2.47, P<0.001), and <6h of sleep duration in comparison with 6 to <7h sleep (OR 2.32, CI 1.18-4.55, P=0.015). The associations of difficulty in sleep initiation, IPAQ classification, current smoking and alcohol intake with IGT/DM were not statistically significant. Conclusions: Our results showed that shorter sleep duration (<6h of sleep duration per night) was associated with a risk of IGT/DM independent of other lifestyle habits and metabolic risk factors.

Original languageEnglish
Pages (from-to)366-372
Number of pages7
JournalJournal of Diabetes Investigation
Volume2
Issue number5
DOIs
Publication statusPublished - 2011 Oct

Fingerprint

Glucose Intolerance
Diabetes Mellitus
Sleep
Odds Ratio
Confidence Intervals
Exercise
Databases
Habits
Meals
Blood Glucose
Life Style
Fasting
Japan
Logistic Models
Smoking
Alcohols
Hypertension

Keywords

  • Diabetes mellitus
  • Impaired glucose tolerance
  • Short sleep duration

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Association of short sleep duration with impaired glucose tolerance or diabetes mellitus. / Katano, Sayuri; Nakamura, Yasuyuki; Nakamura, Aki; Murakami, Yoshitaka; Tanaka, Taichiro; Takebayashi, Toru; Okayama, Akira; Miura, Katsuyuki; Okamura, Tomonori; Ueshima, Hirotsugu.

In: Journal of Diabetes Investigation, Vol. 2, No. 5, 10.2011, p. 366-372.

Research output: Contribution to journalArticle

Katano, S, Nakamura, Y, Nakamura, A, Murakami, Y, Tanaka, T, Takebayashi, T, Okayama, A, Miura, K, Okamura, T & Ueshima, H 2011, 'Association of short sleep duration with impaired glucose tolerance or diabetes mellitus', Journal of Diabetes Investigation, vol. 2, no. 5, pp. 366-372. https://doi.org/10.1111/j.2040-1124.2011.00114.x
Katano, Sayuri ; Nakamura, Yasuyuki ; Nakamura, Aki ; Murakami, Yoshitaka ; Tanaka, Taichiro ; Takebayashi, Toru ; Okayama, Akira ; Miura, Katsuyuki ; Okamura, Tomonori ; Ueshima, Hirotsugu. / Association of short sleep duration with impaired glucose tolerance or diabetes mellitus. In: Journal of Diabetes Investigation. 2011 ; Vol. 2, No. 5. pp. 366-372.
@article{17e60b7d4a974d23af46212e236a773d,
title = "Association of short sleep duration with impaired glucose tolerance or diabetes mellitus",
abstract = "Aims/Introduction: To examine the cross-sectional relationship between sleep duration and impaired glucose tolerance (IGT), including diabetes mellitus (DM), we analyzed a large-scale healthy workers database in Japan. Materials and Methods: We examined the baseline database of 4143 participants (3415 men and 728 women) aged 19-69years. Sleep duration of participants was categorized into four groups: <6, 6 to <7, 7 to <8 and ≥8h. The physical activity of each participant was classified according to the International Physical Activity Questionnaire (IPAQ). We defined IGT including DM (IGT/DM) in the present study according to previous studies as follows: fasting blood sugar level ≥110mg/dL, or if <8h after meals ≥140mg/dL, or on medication for diabetes mellitus, or those diagnosed as having DM. Logistic regression was applied to estimate the odds ratio (OR) to examine the relationship between IGT/DM, sleep duration and other related factors. Results: The number of participants with IGT/DM was 402 (9.7{\%}). The factors that significantly associated with IGT/DM were age (OR 1.08, 95{\%} confidence interval [CI] 1.07-1.10, P<0.001), high blood pressure (OR 1.94, CI 1.52-2.47, P<0.001), and <6h of sleep duration in comparison with 6 to <7h sleep (OR 2.32, CI 1.18-4.55, P=0.015). The associations of difficulty in sleep initiation, IPAQ classification, current smoking and alcohol intake with IGT/DM were not statistically significant. Conclusions: Our results showed that shorter sleep duration (<6h of sleep duration per night) was associated with a risk of IGT/DM independent of other lifestyle habits and metabolic risk factors.",
keywords = "Diabetes mellitus, Impaired glucose tolerance, Short sleep duration",
author = "Sayuri Katano and Yasuyuki Nakamura and Aki Nakamura and Yoshitaka Murakami and Taichiro Tanaka and Toru Takebayashi and Akira Okayama and Katsuyuki Miura and Tomonori Okamura and Hirotsugu Ueshima",
year = "2011",
month = "10",
doi = "10.1111/j.2040-1124.2011.00114.x",
language = "English",
volume = "2",
pages = "366--372",
journal = "Journal of Diabetes Investigation",
issn = "2040-1116",
publisher = "Blackwell Publishing Asia Pty Ltd",
number = "5",

}

TY - JOUR

T1 - Association of short sleep duration with impaired glucose tolerance or diabetes mellitus

AU - Katano, Sayuri

AU - Nakamura, Yasuyuki

AU - Nakamura, Aki

AU - Murakami, Yoshitaka

AU - Tanaka, Taichiro

AU - Takebayashi, Toru

AU - Okayama, Akira

AU - Miura, Katsuyuki

AU - Okamura, Tomonori

AU - Ueshima, Hirotsugu

PY - 2011/10

Y1 - 2011/10

N2 - Aims/Introduction: To examine the cross-sectional relationship between sleep duration and impaired glucose tolerance (IGT), including diabetes mellitus (DM), we analyzed a large-scale healthy workers database in Japan. Materials and Methods: We examined the baseline database of 4143 participants (3415 men and 728 women) aged 19-69years. Sleep duration of participants was categorized into four groups: <6, 6 to <7, 7 to <8 and ≥8h. The physical activity of each participant was classified according to the International Physical Activity Questionnaire (IPAQ). We defined IGT including DM (IGT/DM) in the present study according to previous studies as follows: fasting blood sugar level ≥110mg/dL, or if <8h after meals ≥140mg/dL, or on medication for diabetes mellitus, or those diagnosed as having DM. Logistic regression was applied to estimate the odds ratio (OR) to examine the relationship between IGT/DM, sleep duration and other related factors. Results: The number of participants with IGT/DM was 402 (9.7%). The factors that significantly associated with IGT/DM were age (OR 1.08, 95% confidence interval [CI] 1.07-1.10, P<0.001), high blood pressure (OR 1.94, CI 1.52-2.47, P<0.001), and <6h of sleep duration in comparison with 6 to <7h sleep (OR 2.32, CI 1.18-4.55, P=0.015). The associations of difficulty in sleep initiation, IPAQ classification, current smoking and alcohol intake with IGT/DM were not statistically significant. Conclusions: Our results showed that shorter sleep duration (<6h of sleep duration per night) was associated with a risk of IGT/DM independent of other lifestyle habits and metabolic risk factors.

AB - Aims/Introduction: To examine the cross-sectional relationship between sleep duration and impaired glucose tolerance (IGT), including diabetes mellitus (DM), we analyzed a large-scale healthy workers database in Japan. Materials and Methods: We examined the baseline database of 4143 participants (3415 men and 728 women) aged 19-69years. Sleep duration of participants was categorized into four groups: <6, 6 to <7, 7 to <8 and ≥8h. The physical activity of each participant was classified according to the International Physical Activity Questionnaire (IPAQ). We defined IGT including DM (IGT/DM) in the present study according to previous studies as follows: fasting blood sugar level ≥110mg/dL, or if <8h after meals ≥140mg/dL, or on medication for diabetes mellitus, or those diagnosed as having DM. Logistic regression was applied to estimate the odds ratio (OR) to examine the relationship between IGT/DM, sleep duration and other related factors. Results: The number of participants with IGT/DM was 402 (9.7%). The factors that significantly associated with IGT/DM were age (OR 1.08, 95% confidence interval [CI] 1.07-1.10, P<0.001), high blood pressure (OR 1.94, CI 1.52-2.47, P<0.001), and <6h of sleep duration in comparison with 6 to <7h sleep (OR 2.32, CI 1.18-4.55, P=0.015). The associations of difficulty in sleep initiation, IPAQ classification, current smoking and alcohol intake with IGT/DM were not statistically significant. Conclusions: Our results showed that shorter sleep duration (<6h of sleep duration per night) was associated with a risk of IGT/DM independent of other lifestyle habits and metabolic risk factors.

KW - Diabetes mellitus

KW - Impaired glucose tolerance

KW - Short sleep duration

UR - http://www.scopus.com/inward/record.url?scp=80053987049&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053987049&partnerID=8YFLogxK

U2 - 10.1111/j.2040-1124.2011.00114.x

DO - 10.1111/j.2040-1124.2011.00114.x

M3 - Article

VL - 2

SP - 366

EP - 372

JO - Journal of Diabetes Investigation

JF - Journal of Diabetes Investigation

SN - 2040-1116

IS - 5

ER -