TY - JOUR
T1 - Atypical clinical presentation of crohn’s disease with superior mesenteric vein obstruction and protein-losing enteropathy
AU - Ito, Suguru
AU - Higashiyama, Masaaki
AU - Horiuchi, Kazuki
AU - Mizoguchi, Akinori
AU - Soga, Shigeyoshi
AU - Tanemoto, Rina
AU - Nishii, Shin
AU - Terada, Hisato
AU - Wada, Akinori
AU - Sugihara, Nao
AU - Hanawa, Yoshinori
AU - Furuhashi, Hirotaka
AU - Takajo, Takeshi
AU - Shirakabe, Kazuhiko
AU - Watanabe, Chikako
AU - Komoto, Shunsuke
AU - Tomita, Kengo
AU - Nagao, Shigeaki
AU - Shinozaki, Masami
AU - Nakagawa, Akihiko
AU - Kubota, Michio
AU - Miyagishima, Daisuke
AU - Gotoh, Nobuaki
AU - Miura, Soichiro
AU - Ueno, Hideki
AU - Hokari, Ryota
N1 - Publisher Copyright:
© 2019 The Japanese Society of Internal Medicine.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019
Y1 - 2019
N2 - We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn’s disease (CD). PLE was supposedly induced by both intestinal erosion and thrombosis-related lymphangiectasia, which was histologically proven in his surgically-resected ileal stenosis. Elemental diet and anti-TNFα agent improved his hypoalbuminemia after surgery. The rarity of the simultaneous coexistence of SMV obstruction and PLE and the precedence of these complications over typical abdominal symptoms of CD made the clinical course complex.
AB - We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn’s disease (CD). PLE was supposedly induced by both intestinal erosion and thrombosis-related lymphangiectasia, which was histologically proven in his surgically-resected ileal stenosis. Elemental diet and anti-TNFα agent improved his hypoalbuminemia after surgery. The rarity of the simultaneous coexistence of SMV obstruction and PLE and the precedence of these complications over typical abdominal symptoms of CD made the clinical course complex.
KW - Crohn’s disease (CD)
KW - Mesenteric vein thrombosis
KW - Protein-losing enteropathy (PLE)
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U2 - 10.2169/internalmedicine.1192-18
DO - 10.2169/internalmedicine.1192-18
M3 - Article
C2 - 30210116
AN - SCOPUS:85061024673
VL - 58
SP - 369
EP - 374
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 3
ER -