TY - JOUR
T1 - Atypical polypoid adenomyoma treated by hysteroscopy with photodynamic diagnosis using 5-aminolevulinic acid
T2 - A case report
AU - Matoba, Yusuke
AU - Banno, Kouji
AU - Kobayashi, Yusuke
AU - Kisu, Iori
AU - Aoki, Daisuke
N1 - Funding Information:
This study was supported by a JFE (Japanese Foundation for Research and Promotion of Endoscopy) Grant 2018.
Publisher Copyright:
© 2019 The Authors
PY - 2019/9
Y1 - 2019/9
N2 - Surgical resection for atypical polypoid adenomyoma (APA) is an option for fertility preservation. Due to the high recurrence rate of APA, studies have been conducted to improve total resection of tumors. Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) improves tumor resection, but this has not been applied for APA. The patient was 35-year-old. After initial treatment, the APA lesion did not disappear. We performed hysteroscopic tumor resection using 5-ALA-PDD. Only one PDD-positive lesion was found and histopathologically diagnosed as APA. Other areas were PDD-negative and showed no histopathologic APA or malignant findings. This is the first report of hysteroscopic 5-ALA-PDD for APA. This method makes it easy to identify morbid lesions, and may lead to improved total resection and decreased recurrence.
AB - Surgical resection for atypical polypoid adenomyoma (APA) is an option for fertility preservation. Due to the high recurrence rate of APA, studies have been conducted to improve total resection of tumors. Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) improves tumor resection, but this has not been applied for APA. The patient was 35-year-old. After initial treatment, the APA lesion did not disappear. We performed hysteroscopic tumor resection using 5-ALA-PDD. Only one PDD-positive lesion was found and histopathologically diagnosed as APA. Other areas were PDD-negative and showed no histopathologic APA or malignant findings. This is the first report of hysteroscopic 5-ALA-PDD for APA. This method makes it easy to identify morbid lesions, and may lead to improved total resection and decreased recurrence.
KW - 5-Aminolevulinic acid
KW - Atypical polypoid adenomyoma
KW - Hysteroscopy
KW - Photodynamic diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85068072638&partnerID=8YFLogxK
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U2 - 10.1016/j.pdpdt.2019.06.019
DO - 10.1016/j.pdpdt.2019.06.019
M3 - Article
C2 - 31252140
AN - SCOPUS:85068072638
SN - 1572-1000
VL - 27
SP - 295
EP - 297
JO - Photodiagnosis and Photodynamic Therapy
JF - Photodiagnosis and Photodynamic Therapy
ER -