Abstract
We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjogren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the normal lacrimal gland, suggesting that the CD44 v6 variant exon may be closely associated with the development of LPD in Sjogren's syndrome.
| Original language | English |
|---|---|
| Pages (from-to) | 312-318 |
| Number of pages | 7 |
| Journal | Japanese Journal of Ophthalmology |
| Volume | 41 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1997 Sep |
| Externally published | Yes |
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Keywords
- CD44 splice variant
- Lacrimal gland
- Lymphoproliferative disorder
- Sjogren's syndrome
ASJC Scopus subject areas
- Ophthalmology
Cite this
Augmented expression of CD44 splice variants in lymphoproliferative disorder of the lacrimal gland in Sjogren's syndrome. / Hiraoka, Miki; Saito, Ichiro; Tsubota, Kazuo; Sugai, Susumu; Miyasaka, Nobuyuki.
In: Japanese Journal of Ophthalmology, Vol. 41, No. 5, 09.1997, p. 312-318.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Augmented expression of CD44 splice variants in lymphoproliferative disorder of the lacrimal gland in Sjogren's syndrome
AU - Hiraoka, Miki
AU - Saito, Ichiro
AU - Tsubota, Kazuo
AU - Sugai, Susumu
AU - Miyasaka, Nobuyuki
PY - 1997/9
Y1 - 1997/9
N2 - We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjogren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the normal lacrimal gland, suggesting that the CD44 v6 variant exon may be closely associated with the development of LPD in Sjogren's syndrome.
AB - We explored the involvement of CD44 isoforms in lymphoproliferative disorder (LPD) of the lacrimal gland of a Sjogren's syndrome patient with unilateral LPD. The CD44 variant with the v6 exon was selectively detected from infiltrating lymphocytes in the gland with LPD, but not from infiltrating lymphocytes in the normal lacrimal gland, suggesting that the CD44 v6 variant exon may be closely associated with the development of LPD in Sjogren's syndrome.
KW - CD44 splice variant
KW - Lacrimal gland
KW - Lymphoproliferative disorder
KW - Sjogren's syndrome
UR - http://www.scopus.com/inward/record.url?scp=0030665392&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030665392&partnerID=8YFLogxK
U2 - 10.1016/S0021-5155(97)00072-5
DO - 10.1016/S0021-5155(97)00072-5
M3 - Article
C2 - 9363560
AN - SCOPUS:0030665392
VL - 41
SP - 312
EP - 318
JO - Japanese Journal of Ophthalmology
JF - Japanese Journal of Ophthalmology
SN - 0021-5155
IS - 5
ER -