Auriculol, a cytotoxic oxygenated squalene from the Japanese sea hare Dolabella auricularia: Isolation, stereostructure, and synthesis

Hideo Kigoshi, Takashi Itoh, Takafumi Ogawa, Kenya Ochi, Mayuko Okada, Kiyotake Suenaga, Kiyoyuki Yamada

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Auriculol, a cytotoxic oxygenated squalene, was isolated from the Japanese sea hare Dolabella auricularia, and its stereostructure was elucidated by spectral analysis and organic synthesis.

Original languageEnglish
Pages (from-to)7461-7464
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number42
DOIs
Publication statusPublished - 2001 Oct 15
Externally publishedYes

Keywords

  • Cytotoxicity
  • Dolabella auricularia
  • Isolation
  • Sea hare
  • Stereostructure
  • Synthesis
  • Triterpenoid

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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