Auriculol, a cytotoxic oxygenated squalene from the Japanese sea hare Dolabella auricularia: Isolation, stereostructure, and synthesis

Hideo Kigoshi, Takashi Itoh, Takafumi Ogawa, Kenya Ochi, Mayuko Okada, Kiyotake Suenaga, Kiyoyuki Yamada

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Auriculol, a cytotoxic oxygenated squalene, was isolated from the Japanese sea hare Dolabella auricularia, and its stereostructure was elucidated by spectral analysis and organic synthesis.

Original languageEnglish
Pages (from-to)7461-7464
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number42
DOIs
Publication statusPublished - 2001 Oct 15
Externally publishedYes

Fingerprint

Squalene
Hares
Synthetic Chemistry Techniques
Oceans and Seas
Spectrum analysis

Keywords

  • Cytotoxicity
  • Dolabella auricularia
  • Isolation
  • Sea hare
  • Stereostructure
  • Synthesis
  • Triterpenoid

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Auriculol, a cytotoxic oxygenated squalene from the Japanese sea hare Dolabella auricularia : Isolation, stereostructure, and synthesis. / Kigoshi, Hideo; Itoh, Takashi; Ogawa, Takafumi; Ochi, Kenya; Okada, Mayuko; Suenaga, Kiyotake; Yamada, Kiyoyuki.

In: Tetrahedron Letters, Vol. 42, No. 42, 15.10.2001, p. 7461-7464.

Research output: Contribution to journalArticle

Kigoshi, Hideo ; Itoh, Takashi ; Ogawa, Takafumi ; Ochi, Kenya ; Okada, Mayuko ; Suenaga, Kiyotake ; Yamada, Kiyoyuki. / Auriculol, a cytotoxic oxygenated squalene from the Japanese sea hare Dolabella auricularia : Isolation, stereostructure, and synthesis. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 42. pp. 7461-7464.
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