Aurilol, a cytotoxic bromotriterpene isolated from the sea hare Dolabella auricularia

Kiyotake Suenaga, T. Shibata, N. Takada, H. Kigoshi, K. Yamada

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Aurilol (1), a novel cytotoxic bromotriterpene, was isolated from the sea hare Dolabella auricularia. The structure of 1, including the absolute stereochemistry of the five stereocenters, was determined by spectroscopic and chemical analyses. Aurilol (1) exhibited cytotoxicity against HeLa S3 cells with an IC50 of 4.3 μg/mL.

Original languageEnglish
Pages (from-to)515-518
Number of pages4
JournalJournal of Natural Products
Volume61
Issue number4
DOIs
Publication statusPublished - 1998
Externally publishedYes

Fingerprint

Hares
stereochemistry
Oceans and Seas
inhibitory concentration 50
cytotoxicity
Stereochemistry
Cytotoxicity
HeLa Cells
Inhibitory Concentration 50
cells
Dolabella auricularia
Anaspidea
aurilol

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

Aurilol, a cytotoxic bromotriterpene isolated from the sea hare Dolabella auricularia. / Suenaga, Kiyotake; Shibata, T.; Takada, N.; Kigoshi, H.; Yamada, K.

In: Journal of Natural Products, Vol. 61, No. 4, 1998, p. 515-518.

Research output: Contribution to journalArticle

Suenaga, Kiyotake ; Shibata, T. ; Takada, N. ; Kigoshi, H. ; Yamada, K. / Aurilol, a cytotoxic bromotriterpene isolated from the sea hare Dolabella auricularia. In: Journal of Natural Products. 1998 ; Vol. 61, No. 4. pp. 515-518.
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