Aurilol, a cytotoxic bromotriterpene isolated from the sea hare Dolabella auricularia

K. Suenaga, T. Shibata, N. Takada, H. Kigoshi, K. Yamada

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28 Citations (Scopus)

Abstract

Aurilol (1), a novel cytotoxic bromotriterpene, was isolated from the sea hare Dolabella auricularia. The structure of 1, including the absolute stereochemistry of the five stereocenters, was determined by spectroscopic and chemical analyses. Aurilol (1) exhibited cytotoxicity against HeLa S3 cells with an IC50 of 4.3 μg/mL.

Original languageEnglish
Pages (from-to)515-518
Number of pages4
JournalJournal of Natural Products
Volume61
Issue number4
DOIs
Publication statusPublished - 1998 Jan 1

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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