Autologous serum eye drops for dry eye after LASIK

Tomoko Noda-Tsuruya, Naoko Asano-Kato, Ikuko Toda, Kazuo Tsubota

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

PURPOSE: To evaluate the efficacy of autologous serum eye drops for dry eye after LASIK in a prospective, randomized study. METHODS: Fifty-four eyes of 27 male patients who underwent LASIK were divided into two groups; patients who used autologous serum eye drops and those who used artificial tears postoperatively. Schirmer test with anesthesia, tear break-up time (BUT), and rose bengal and fluorescein staining for the ocular surface were prospectively compared between the groups. All values were also compared before and after surgery (at 1 week [except for Schirmer test], 1 month, 3 months, and 6 months) in each group. RESULTS: Tear BUT was greater in the autologous serum eye drops group than in the artificial tears group at 6 months postoperatively. Rose bengal score was lower in patients using autologous serum eye drops than in patients using artificial tears at 1 month and 3 months postoperatively. No significant difference was noted between patients using autologous serum eye drops and patients using artificial tears in the value of Schirmer test with anesthesia and fluorescein scores. In the autologous serum eye drops group, tear BUT was increased at 3 months after LASIK, rose bengal score was lower at 1 month and 3 months, and fluorescein score was lower at 1 month after LASIK compared to preoperative values, respectively. In the artificial tears group, all values (Schirmer test, tear BUT, rose bengal score, and fluorescein score) showed no differences between before and after LASIK. No differences were noted in the subjective scores for dryness between the autologous serum eye drops and artificial tears groups. CONCLUSIONS: The autologous serum eye drops group showed prolongation of the tear BUT and a reduction in rose bengal staining score.

Original languageEnglish
Pages (from-to)61-66
Number of pages6
JournalJournal of Refractive Surgery
Volume22
Issue number1
Publication statusPublished - 2006 Jan

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Laser In Situ Keratomileusis
Ophthalmic Solutions
Rose Bengal
Tears
Fluorescein
Serum
Anesthesia
Staining and Labeling
Lubricant Eye Drops
Prospective Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Noda-Tsuruya, T., Asano-Kato, N., Toda, I., & Tsubota, K. (2006). Autologous serum eye drops for dry eye after LASIK. Journal of Refractive Surgery, 22(1), 61-66.

Autologous serum eye drops for dry eye after LASIK. / Noda-Tsuruya, Tomoko; Asano-Kato, Naoko; Toda, Ikuko; Tsubota, Kazuo.

In: Journal of Refractive Surgery, Vol. 22, No. 1, 01.2006, p. 61-66.

Research output: Contribution to journalArticle

Noda-Tsuruya, T, Asano-Kato, N, Toda, I & Tsubota, K 2006, 'Autologous serum eye drops for dry eye after LASIK', Journal of Refractive Surgery, vol. 22, no. 1, pp. 61-66.
Noda-Tsuruya T, Asano-Kato N, Toda I, Tsubota K. Autologous serum eye drops for dry eye after LASIK. Journal of Refractive Surgery. 2006 Jan;22(1):61-66.
Noda-Tsuruya, Tomoko ; Asano-Kato, Naoko ; Toda, Ikuko ; Tsubota, Kazuo. / Autologous serum eye drops for dry eye after LASIK. In: Journal of Refractive Surgery. 2006 ; Vol. 22, No. 1. pp. 61-66.
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