Bacterial flora of ex-germfree mice after oral inoculation of feces from various species of conventional animals.

K. Maejima, J. Sasaki, Kouji Shimoda, T. Kurosawa

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Emulsions of fresh feces from a conventional mouse, rabbit, dog or cynomolgus monkey were administered orally to germfree and conventional ICR mice. Various fecal floras bearing a striking resemblance in pattern to those in the inoculant became established in the inoculated ex-germfree mice. Reinoculation of these ex-germfree mice with fecal emulsions from a conventional mouse made 21 days after the original inoculation (conventionalization) led to alteration of their floras to the indigenous pattern of conventional mice. The administration of feces from the conventional animals of different species did not appreciably modify the fecal flora of conventional mice. The results indicate that intestinal flora of animals is determined in the first stage by that of the contaminants, but this would be altered later under the predominant influence of the various host factors.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalJikken dobutsu. Experimental animals
Volume30
Issue number2
Publication statusPublished - 1981 Apr
Externally publishedYes

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Emulsions
Feces
oral administration
Animals
Bearings (structural)
feces
flora
mice
animals
Impurities
emulsions
Inbred ICR Mouse
Macaca fascicularis
intestinal microorganisms
Dogs
Rabbits
rabbits
dogs

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bacterial flora of ex-germfree mice after oral inoculation of feces from various species of conventional animals. / Maejima, K.; Sasaki, J.; Shimoda, Kouji; Kurosawa, T.

In: Jikken dobutsu. Experimental animals, Vol. 30, No. 2, 04.1981, p. 157-160.

Research output: Contribution to journalArticle

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