Balance between acute graft-versus-host disease and graft-versus-tumor effect after reduced-intensity transplantation for metastatic renal cell carcinoma

Akiko Hori, Masahiro Kami, Sung Won Kim, Atsushi Makimoto, Ryuji Tanosaki, Yoichi Takaue

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We describe a patient who had received reduced-intensity stem cell transplantation (RIST) for metastatic renal cell carcinoma (RCC). A 37-year-old man developed rapid progression of RCC during steroid therapy for immune-mediated thrombocytopenia and graft-versus-host disease (GVHD). After discontinuation of corticosteroid, RCC achieved long stable disease with the presence of chronic GVHD, despite low dose of prednisolone. This case suggests the impact of immunosuppression on progression of metastatic RCC after RIST.

Original languageEnglish
Pages (from-to)276-278
Number of pages3
JournalHematology Journal
Volume5
Issue number3
DOIs
Publication statusPublished - 2004

Keywords

  • Acute graft-versus-host diasease
  • Corticosteroid
  • Graft-versus-tumor effect
  • Reduced-intensity stem cell transplantation
  • Renal cell carcinoma

ASJC Scopus subject areas

  • Hematology

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