Basic study on nanofabrication of biodegradable plastics applying biochemical machining

Satoshi Ikeda, Yasuhiro Kakinuma

Research output: Contribution to journalArticle

Abstract

Plastics are regarded as proper materials for microfluidic chips, and, in particular, biodegradable plastics will be more appropriate from the viewpoint of environmental friendliness. In addition, when they are utilized as chip substrate, biochemical machining can be applied. Biochemical machining is a process, which utilizes enzymatic biodegradation. This paper describes studies on application of biochemical machining to nanofabrication of poly(l-lactic acid) (PLLA), which is one of the most widely used biodegradable plastics industrially. The degradation performance of enzyme (proteinase K) was experimentally evaluated to extrapolate a suitable condition for nanofabrication. Additionally, in order to make arbitrary channels with nano-order depth on PLLA, mask fabrication was proposed. It is a fabrication method to control degraded regions and obtain desired shapes with a mask, which has penetrating grooves. Using this method, we achieved fabrication of straight grooves with nano-scale depth. In conclusion, it is clear that biochemical machining can realize an effective process of arbitrarily shaped nanogrooves on PLLA.

Original languageEnglish
Pages (from-to)440-446
Number of pages7
JournalPrecision Engineering
Volume35
Issue number3
DOIs
Publication statusPublished - 2011 Jul

Fingerprint

Nanotechnology
Machining
Lactic acid
Plastics
Fabrication
Masks
Biodegradation
Microfluidics
Enzymes
Degradation
Substrates

Keywords

  • Biochemical machining
  • Biodegradable plastic
  • Enzymatic hydrolysis
  • Nanofabrication
  • PLLA
  • Poly(l-lactide)
  • Proteinase K

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Basic study on nanofabrication of biodegradable plastics applying biochemical machining. / Ikeda, Satoshi; Kakinuma, Yasuhiro.

In: Precision Engineering, Vol. 35, No. 3, 07.2011, p. 440-446.

Research output: Contribution to journalArticle

@article{9c656f2a6237432c83b78bef14732710,
title = "Basic study on nanofabrication of biodegradable plastics applying biochemical machining",
abstract = "Plastics are regarded as proper materials for microfluidic chips, and, in particular, biodegradable plastics will be more appropriate from the viewpoint of environmental friendliness. In addition, when they are utilized as chip substrate, biochemical machining can be applied. Biochemical machining is a process, which utilizes enzymatic biodegradation. This paper describes studies on application of biochemical machining to nanofabrication of poly(l-lactic acid) (PLLA), which is one of the most widely used biodegradable plastics industrially. The degradation performance of enzyme (proteinase K) was experimentally evaluated to extrapolate a suitable condition for nanofabrication. Additionally, in order to make arbitrary channels with nano-order depth on PLLA, mask fabrication was proposed. It is a fabrication method to control degraded regions and obtain desired shapes with a mask, which has penetrating grooves. Using this method, we achieved fabrication of straight grooves with nano-scale depth. In conclusion, it is clear that biochemical machining can realize an effective process of arbitrarily shaped nanogrooves on PLLA.",
keywords = "Biochemical machining, Biodegradable plastic, Enzymatic hydrolysis, Nanofabrication, PLLA, Poly(l-lactide), Proteinase K",
author = "Satoshi Ikeda and Yasuhiro Kakinuma",
year = "2011",
month = "7",
doi = "10.1016/j.precisioneng.2011.02.007",
language = "English",
volume = "35",
pages = "440--446",
journal = "Precision Engineering",
issn = "0141-6359",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Basic study on nanofabrication of biodegradable plastics applying biochemical machining

AU - Ikeda, Satoshi

AU - Kakinuma, Yasuhiro

PY - 2011/7

Y1 - 2011/7

N2 - Plastics are regarded as proper materials for microfluidic chips, and, in particular, biodegradable plastics will be more appropriate from the viewpoint of environmental friendliness. In addition, when they are utilized as chip substrate, biochemical machining can be applied. Biochemical machining is a process, which utilizes enzymatic biodegradation. This paper describes studies on application of biochemical machining to nanofabrication of poly(l-lactic acid) (PLLA), which is one of the most widely used biodegradable plastics industrially. The degradation performance of enzyme (proteinase K) was experimentally evaluated to extrapolate a suitable condition for nanofabrication. Additionally, in order to make arbitrary channels with nano-order depth on PLLA, mask fabrication was proposed. It is a fabrication method to control degraded regions and obtain desired shapes with a mask, which has penetrating grooves. Using this method, we achieved fabrication of straight grooves with nano-scale depth. In conclusion, it is clear that biochemical machining can realize an effective process of arbitrarily shaped nanogrooves on PLLA.

AB - Plastics are regarded as proper materials for microfluidic chips, and, in particular, biodegradable plastics will be more appropriate from the viewpoint of environmental friendliness. In addition, when they are utilized as chip substrate, biochemical machining can be applied. Biochemical machining is a process, which utilizes enzymatic biodegradation. This paper describes studies on application of biochemical machining to nanofabrication of poly(l-lactic acid) (PLLA), which is one of the most widely used biodegradable plastics industrially. The degradation performance of enzyme (proteinase K) was experimentally evaluated to extrapolate a suitable condition for nanofabrication. Additionally, in order to make arbitrary channels with nano-order depth on PLLA, mask fabrication was proposed. It is a fabrication method to control degraded regions and obtain desired shapes with a mask, which has penetrating grooves. Using this method, we achieved fabrication of straight grooves with nano-scale depth. In conclusion, it is clear that biochemical machining can realize an effective process of arbitrarily shaped nanogrooves on PLLA.

KW - Biochemical machining

KW - Biodegradable plastic

KW - Enzymatic hydrolysis

KW - Nanofabrication

KW - PLLA

KW - Poly(l-lactide)

KW - Proteinase K

UR - http://www.scopus.com/inward/record.url?scp=79955807341&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955807341&partnerID=8YFLogxK

U2 - 10.1016/j.precisioneng.2011.02.007

DO - 10.1016/j.precisioneng.2011.02.007

M3 - Article

AN - SCOPUS:79955807341

VL - 35

SP - 440

EP - 446

JO - Precision Engineering

JF - Precision Engineering

SN - 0141-6359

IS - 3

ER -