Behavioral and psychological symptoms of dementia in untreated Alzheimer's disease patients

Atsushi Hamuro, Hiroshi Isono, Yuichi Sugai, Shigeo Torii, Nobuo Furuta, Masaru Mimura, Kunitoshi Kamijima

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: To ascertain the prevalence of psychotic symptoms and behavioral disturbances of dementia patients is useful for families and health care professionals in order to anticipate the progression of Alzheimer's disease (AD) and to recognize deterioration. This study aimed to determine whether behavioral and psychological symptoms of dementia (BPSD) are related to severity of untreated AD. Methods: Two hundred and two patients were classified into three groups by Functional Assessment Staging score as follows: mild group (n=92) was at stages 3 or 4; moderate group (n =80) was at stage 5; and severe group (n=30) was at stages 6 or 7. We then compared the prevalence of BPSD among the groups. Psychiatric symptoms of BPSD were defined as including hallucinations, delusions, delusional misidentification syndrome and depressive mood; while behavioral disturbances included physical aggression, wandering, adverse sleep and hyperphagia. Results: In our study, depressive mood, physical aggression and wandering were statistically associated with the severity of AD. Conclusion: These results are meaningful for caregivers in helping them to understand the anticipated progression of AD and to recognize deterioration. In the care of AD patients, it is necessary to be aware of characteristics of each BPSD.

Original languageEnglish
Pages (from-to)4-7
Number of pages4
JournalPsychogeriatrics
Volume7
Issue number1
DOIs
Publication statusPublished - 2007 Mar
Externally publishedYes

Fingerprint

Behavioral Symptoms
Dementia
Alzheimer Disease
Psychology
Aggression
Hyperphagia
Delusions
Family Health
Hallucinations
Depressive Disorder
Caregivers
Psychiatry
Sleep
Delivery of Health Care

Keywords

  • Alzheimer's disease
  • BPSD
  • Functional assessment staging
  • Severity
  • Untreated patients

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Behavioral and psychological symptoms of dementia in untreated Alzheimer's disease patients. / Hamuro, Atsushi; Isono, Hiroshi; Sugai, Yuichi; Torii, Shigeo; Furuta, Nobuo; Mimura, Masaru; Kamijima, Kunitoshi.

In: Psychogeriatrics, Vol. 7, No. 1, 03.2007, p. 4-7.

Research output: Contribution to journalArticle

Hamuro, Atsushi ; Isono, Hiroshi ; Sugai, Yuichi ; Torii, Shigeo ; Furuta, Nobuo ; Mimura, Masaru ; Kamijima, Kunitoshi. / Behavioral and psychological symptoms of dementia in untreated Alzheimer's disease patients. In: Psychogeriatrics. 2007 ; Vol. 7, No. 1. pp. 4-7.
@article{a4f6eade43364e9eaa357e60fd46e4be,
title = "Behavioral and psychological symptoms of dementia in untreated Alzheimer's disease patients",
abstract = "Background: To ascertain the prevalence of psychotic symptoms and behavioral disturbances of dementia patients is useful for families and health care professionals in order to anticipate the progression of Alzheimer's disease (AD) and to recognize deterioration. This study aimed to determine whether behavioral and psychological symptoms of dementia (BPSD) are related to severity of untreated AD. Methods: Two hundred and two patients were classified into three groups by Functional Assessment Staging score as follows: mild group (n=92) was at stages 3 or 4; moderate group (n =80) was at stage 5; and severe group (n=30) was at stages 6 or 7. We then compared the prevalence of BPSD among the groups. Psychiatric symptoms of BPSD were defined as including hallucinations, delusions, delusional misidentification syndrome and depressive mood; while behavioral disturbances included physical aggression, wandering, adverse sleep and hyperphagia. Results: In our study, depressive mood, physical aggression and wandering were statistically associated with the severity of AD. Conclusion: These results are meaningful for caregivers in helping them to understand the anticipated progression of AD and to recognize deterioration. In the care of AD patients, it is necessary to be aware of characteristics of each BPSD.",
keywords = "Alzheimer's disease, BPSD, Functional assessment staging, Severity, Untreated patients",
author = "Atsushi Hamuro and Hiroshi Isono and Yuichi Sugai and Shigeo Torii and Nobuo Furuta and Masaru Mimura and Kunitoshi Kamijima",
year = "2007",
month = "3",
doi = "10.1111/j.1479-8301.2006.00153.x",
language = "English",
volume = "7",
pages = "4--7",
journal = "Psychogeriatrics",
issn = "1346-3500",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Behavioral and psychological symptoms of dementia in untreated Alzheimer's disease patients

AU - Hamuro, Atsushi

AU - Isono, Hiroshi

AU - Sugai, Yuichi

AU - Torii, Shigeo

AU - Furuta, Nobuo

AU - Mimura, Masaru

AU - Kamijima, Kunitoshi

PY - 2007/3

Y1 - 2007/3

N2 - Background: To ascertain the prevalence of psychotic symptoms and behavioral disturbances of dementia patients is useful for families and health care professionals in order to anticipate the progression of Alzheimer's disease (AD) and to recognize deterioration. This study aimed to determine whether behavioral and psychological symptoms of dementia (BPSD) are related to severity of untreated AD. Methods: Two hundred and two patients were classified into three groups by Functional Assessment Staging score as follows: mild group (n=92) was at stages 3 or 4; moderate group (n =80) was at stage 5; and severe group (n=30) was at stages 6 or 7. We then compared the prevalence of BPSD among the groups. Psychiatric symptoms of BPSD were defined as including hallucinations, delusions, delusional misidentification syndrome and depressive mood; while behavioral disturbances included physical aggression, wandering, adverse sleep and hyperphagia. Results: In our study, depressive mood, physical aggression and wandering were statistically associated with the severity of AD. Conclusion: These results are meaningful for caregivers in helping them to understand the anticipated progression of AD and to recognize deterioration. In the care of AD patients, it is necessary to be aware of characteristics of each BPSD.

AB - Background: To ascertain the prevalence of psychotic symptoms and behavioral disturbances of dementia patients is useful for families and health care professionals in order to anticipate the progression of Alzheimer's disease (AD) and to recognize deterioration. This study aimed to determine whether behavioral and psychological symptoms of dementia (BPSD) are related to severity of untreated AD. Methods: Two hundred and two patients were classified into three groups by Functional Assessment Staging score as follows: mild group (n=92) was at stages 3 or 4; moderate group (n =80) was at stage 5; and severe group (n=30) was at stages 6 or 7. We then compared the prevalence of BPSD among the groups. Psychiatric symptoms of BPSD were defined as including hallucinations, delusions, delusional misidentification syndrome and depressive mood; while behavioral disturbances included physical aggression, wandering, adverse sleep and hyperphagia. Results: In our study, depressive mood, physical aggression and wandering were statistically associated with the severity of AD. Conclusion: These results are meaningful for caregivers in helping them to understand the anticipated progression of AD and to recognize deterioration. In the care of AD patients, it is necessary to be aware of characteristics of each BPSD.

KW - Alzheimer's disease

KW - BPSD

KW - Functional assessment staging

KW - Severity

KW - Untreated patients

UR - http://www.scopus.com/inward/record.url?scp=33847762718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33847762718&partnerID=8YFLogxK

U2 - 10.1111/j.1479-8301.2006.00153.x

DO - 10.1111/j.1479-8301.2006.00153.x

M3 - Article

AN - SCOPUS:33847762718

VL - 7

SP - 4

EP - 7

JO - Psychogeriatrics

JF - Psychogeriatrics

SN - 1346-3500

IS - 1

ER -