Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy

Research output: Contribution to journalArticle

Abstract

A 53-year-old woman with metastatic esthesioneuroblastoma was referred for FDG PET/CT imaging. FDG PET/CT showed symmetrical uptake in bilaterally enlarged adrenal glands, in addition to abnormal uptake in bone and lymph node metastases. 111In-pentetreotide scintigraphy was further performed and revealed the lack of adrenal uptake. The patient's serum adrenocorticotropic hormone (ACTH) level was extremely high, suggesting that hyperplastic condition in the adrenal glands due to ACTH stimulation from the metastatic esthesioneuroblastoma was responsible for increased FDG uptake. The combination of FDG PET and 111In-pentetreotide scintigraphy was useful for the pathophysiological evaluation of ACTH-secreting esthesioneuroblastoma.

Original languageEnglish
Pages (from-to)452-453
Number of pages2
JournalClinical Nuclear Medicine
Volume43
Issue number6
DOIs
Publication statusPublished - 2018 Jun 1

Fingerprint

Olfactory Esthesioneuroblastoma
Radionuclide Imaging
Adrenocorticotropic Hormone
Hyperplasia
Adrenal Glands
Lymph Nodes
Neoplasm Metastasis
Bone and Bones
Serum
pentetreotide

Keywords

  • In pentetreotide scintigraphy
  • ACTH-secreting esthesioneuroblastoma
  • adrenal hyperplasia
  • FDG PET

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Bilateral Adrenal Hyperplasia Due to Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma on FDG PET and 111In-Pentetreotide Scintigraphy",
abstract = "A 53-year-old woman with metastatic esthesioneuroblastoma was referred for FDG PET/CT imaging. FDG PET/CT showed symmetrical uptake in bilaterally enlarged adrenal glands, in addition to abnormal uptake in bone and lymph node metastases. 111In-pentetreotide scintigraphy was further performed and revealed the lack of adrenal uptake. The patient's serum adrenocorticotropic hormone (ACTH) level was extremely high, suggesting that hyperplastic condition in the adrenal glands due to ACTH stimulation from the metastatic esthesioneuroblastoma was responsible for increased FDG uptake. The combination of FDG PET and 111In-pentetreotide scintigraphy was useful for the pathophysiological evaluation of ACTH-secreting esthesioneuroblastoma.",
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author = "Yoji Matsusaka and Tadaki Nakahara and Isao Kurihara and Yu Iwabuchi and Masahiro Jinzaki",
year = "2018",
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AU - Nakahara, Tadaki

AU - Kurihara, Isao

AU - Iwabuchi, Yu

AU - Jinzaki, Masahiro

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