Binding affinity of GM3 lactone for influenza virus

Toshinori Sato, Megumi Ishii, Fuyuka Ohtake, Kyosuke Nagata, Takashi Terabayashi, Yasuhiro Kawanishi, Yoshio Okahata

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We investigated the interaction of GM3 lactone with influenza virus. The specific bindings of influenza virus and its hemagglutinin to GM3 lactone-containing mixed monolayers were studied by using a quartz-crystal microbalance. It has been known that gangliosides as receptors for influenza virus are also substrates for virus neuraminidase. GM3 lactone, however, was found to bind to influenza virus hemagglutinin, but not to be substrate for virus neuraminidase.

Original languageEnglish
Pages (from-to)223-227
Number of pages5
JournalGlycoconjugate Journal
Volume16
Issue number3
DOIs
Publication statusPublished - 1999
Externally publishedYes

Fingerprint

Orthomyxoviridae
Viruses
Hemagglutinins
Neuraminidase
Quartz Crystal Microbalance Techniques
Gangliosides
Quartz crystal microbalances
Substrates
ganglioside GM3 lactone
Monolayers

Keywords

  • Air-water interface monolayer
  • GM3
  • GM3 lactone
  • Hemagglutinin
  • Influenza virus
  • Quartz-crystal microbalance

ASJC Scopus subject areas

  • Biochemistry

Cite this

Sato, T., Ishii, M., Ohtake, F., Nagata, K., Terabayashi, T., Kawanishi, Y., & Okahata, Y. (1999). Binding affinity of GM3 lactone for influenza virus. Glycoconjugate Journal, 16(3), 223-227. https://doi.org/10.1023/A:1007028421092

Binding affinity of GM3 lactone for influenza virus. / Sato, Toshinori; Ishii, Megumi; Ohtake, Fuyuka; Nagata, Kyosuke; Terabayashi, Takashi; Kawanishi, Yasuhiro; Okahata, Yoshio.

In: Glycoconjugate Journal, Vol. 16, No. 3, 1999, p. 223-227.

Research output: Contribution to journalArticle

Sato, T, Ishii, M, Ohtake, F, Nagata, K, Terabayashi, T, Kawanishi, Y & Okahata, Y 1999, 'Binding affinity of GM3 lactone for influenza virus', Glycoconjugate Journal, vol. 16, no. 3, pp. 223-227. https://doi.org/10.1023/A:1007028421092
Sato T, Ishii M, Ohtake F, Nagata K, Terabayashi T, Kawanishi Y et al. Binding affinity of GM3 lactone for influenza virus. Glycoconjugate Journal. 1999;16(3):223-227. https://doi.org/10.1023/A:1007028421092
Sato, Toshinori ; Ishii, Megumi ; Ohtake, Fuyuka ; Nagata, Kyosuke ; Terabayashi, Takashi ; Kawanishi, Yasuhiro ; Okahata, Yoshio. / Binding affinity of GM3 lactone for influenza virus. In: Glycoconjugate Journal. 1999 ; Vol. 16, No. 3. pp. 223-227.
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