Biological activities of phenolic oligomers (I) relationship between the degree of addition-condensation of phenolic oligomers and their antimicrobial activity

T. Uchibori, K. Kawada, S. Watanabe, Kouichi Asakura, S. Matsumura, S. Yoshikawa

Research output: Contribution to journalArticle

Abstract

A series of methylene-bridged phenolic oligomers was prepared and the minimal inhibitory concentrations against bacteria and fungi were determined by agar dilution method. These compounds proved to be greatly effective against gram-positive bacteria and fungi. Homogeneous all ortho methylene-bridged phenolic oligomers were synthesized and the effect of the degree of addition-condensation on antimicrobial potency was examined. Of the homogeneous oligomers, tetramers were the most active against gram-positive bacteria, and trimers showed good antimicrobial activity against fungi.

Original languageEnglish
Pages (from-to)215-218
Number of pages4
JournalJournal of Antibacterial and Antifungal Agents, Japan
Volume18
Issue number5
Publication statusPublished - 1990
Externally publishedYes

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Fungi
Gram-Positive Bacteria
Agar
Bacteria

ASJC Scopus subject areas

  • Microbiology

Cite this

Biological activities of phenolic oligomers (I) relationship between the degree of addition-condensation of phenolic oligomers and their antimicrobial activity. / Uchibori, T.; Kawada, K.; Watanabe, S.; Asakura, Kouichi; Matsumura, S.; Yoshikawa, S.

In: Journal of Antibacterial and Antifungal Agents, Japan, Vol. 18, No. 5, 1990, p. 215-218.

Research output: Contribution to journalArticle

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AU - Asakura, Kouichi

AU - Matsumura, S.

AU - Yoshikawa, S.

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