Biological in vitro evaluations of three-dimensional scaffold developed from single-crystal apatite fibers for tissue engineering of bone

M. Aizawa, H. Shinoda, H. Uchida, I. Okada, T. J. Fujimi, N. Kanzawa, H. Morisue, M. Matsumoto, Y. Toyama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The biological properties of using two kinds of cells, MC3t3-E1 of an osteoblastic cell line and the rat bone-marrow cell (RBMC) as mesenchymal stem cell model were discussed. The HAp fiber was synthesized via a homogeneous precipitation method using urea. The HAp fiber was mixed with the spherical carbon beads having a diameter of ∼ 150 μm in the mixed solvent. The single HAp phase was present in the S0, S1000, and S2000 scaffolds with porosity of 95% over. The results show that the high porosity and large pore size fulfilled by S2000 could provide an excellent environment for enhancing bone marrow cell activity.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004 Dec 1
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period04/5/1704/5/21

ASJC Scopus subject areas

  • Engineering(all)

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    Aizawa, M., Shinoda, H., Uchida, H., Okada, I., Fujimi, T. J., Kanzawa, N., Morisue, H., Matsumoto, M., & Toyama, Y. (2004). Biological in vitro evaluations of three-dimensional scaffold developed from single-crystal apatite fibers for tissue engineering of bone. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).