Biologically active constituents of Arnebia euchroma

Structure of arnebinol, an Ansa-Type monoterpenylbenzenoid with inhibitory activity on prostaglandin biosynthesis

X. S. Yao, Y. Ebizuka, H. Noguchi, F. Kiuchi, Fumiyuki Kiuchi, Y. Iitaka, H. Seto, U. Sankawa

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Three phenolic compounds were isolated from the roots of Arnebia euchroma as inhibitors of in vitro prostaglandin biosynthesis. Two known compounds were identified as shikonofurans and des-O-methyllasiodiplodin. The other new compound was named arnebinol and its structure was elucidated as a novel ansa-type monoterpenylbenzenoid derivative.

Original languageEnglish
Pages (from-to)2956-2961
Number of pages6
JournalChemical and Pharmaceutical Bulletin
Volume39
Issue number11
Publication statusPublished - 1991
Externally publishedYes

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Boraginaceae
Biosynthesis
Prostaglandins
Derivatives
arnebinol
In Vitro Techniques

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Chemistry(all)
  • Pharmacology

Cite this

Biologically active constituents of Arnebia euchroma : Structure of arnebinol, an Ansa-Type monoterpenylbenzenoid with inhibitory activity on prostaglandin biosynthesis. / Yao, X. S.; Ebizuka, Y.; Noguchi, H.; Kiuchi, F.; Kiuchi, Fumiyuki; Iitaka, Y.; Seto, H.; Sankawa, U.

In: Chemical and Pharmaceutical Bulletin, Vol. 39, No. 11, 1991, p. 2956-2961.

Research output: Contribution to journalArticle

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AU - Seto, H.

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