Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

Ryo Nishihara, Hideyuki Suzuki, Emi Hoshino, Sakura Suganuma, Moritoshi Sato, Tsuyoshi Saitoh, Shigeru Nishiyama, Naoko Iwasawa, Daniel Citterio, Koji Suzuki

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives with superior optical properties compared to hitherto reported compounds. This journal is

Original languageEnglish
Pages (from-to)391-394
Number of pages4
JournalChemical Communications
Volume51
Issue number2
DOIs
Publication statusPublished - 2015 Jan 7

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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  • Cite this

    Nishihara, R., Suzuki, H., Hoshino, E., Suganuma, S., Sato, M., Saitoh, T., Nishiyama, S., Iwasawa, N., Citterio, D., & Suzuki, K. (2015). Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution. Chemical Communications, 51(2), 391-394. https://doi.org/10.1039/c4cc06886f