Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

Ryo Nishihara, Hideyuki Suzuki, Emi Hoshino, Sakura Suganuma, Moritoshi Sato, Tsuyoshi Saitoh, Shigeru Nishiyama, Naoko Iwasawa, Daniel Citterio, Koji Suzuki

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives with superior optical properties compared to hitherto reported compounds. This journal is

Original languageEnglish
Pages (from-to)391-394
Number of pages4
JournalChemical Communications
Volume51
Issue number2
DOIs
Publication statusPublished - 2015 Jan 7

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Substitution reactions
Renilla Luciferases
Bioluminescence
Derivatives
Optical properties
coelenterazine

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

Cite this

Nishihara, R., Suzuki, H., Hoshino, E., Suganuma, S., Sato, M., Saitoh, T., ... Suzuki, K. (2015). Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution. Chemical Communications, 51(2), 391-394. https://doi.org/10.1039/c4cc06886f

Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution. / Nishihara, Ryo; Suzuki, Hideyuki; Hoshino, Emi; Suganuma, Sakura; Sato, Moritoshi; Saitoh, Tsuyoshi; Nishiyama, Shigeru; Iwasawa, Naoko; Citterio, Daniel; Suzuki, Koji.

In: Chemical Communications, Vol. 51, No. 2, 07.01.2015, p. 391-394.

Research output: Contribution to journalArticle

Nishihara, R, Suzuki, H, Hoshino, E, Suganuma, S, Sato, M, Saitoh, T, Nishiyama, S, Iwasawa, N, Citterio, D & Suzuki, K 2015, 'Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution', Chemical Communications, vol. 51, no. 2, pp. 391-394. https://doi.org/10.1039/c4cc06886f
Nishihara R, Suzuki H, Hoshino E, Suganuma S, Sato M, Saitoh T et al. Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution. Chemical Communications. 2015 Jan 7;51(2):391-394. https://doi.org/10.1039/c4cc06886f
Nishihara, Ryo ; Suzuki, Hideyuki ; Hoshino, Emi ; Suganuma, Sakura ; Sato, Moritoshi ; Saitoh, Tsuyoshi ; Nishiyama, Shigeru ; Iwasawa, Naoko ; Citterio, Daniel ; Suzuki, Koji. / Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution. In: Chemical Communications. 2015 ; Vol. 51, No. 2. pp. 391-394.
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