Biselides A-E: Novel polyketides from the Okinawan ascidian Didemnidae sp.

Toshiaki Teruya, Kiyotake Suenaga, Sakiko Maruyama, Mineko Kurotaki, Hideo Kigoshi

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31 Citations (Scopus)

Abstract

Five new polyketides, biselides A (1), B (2), C (3), D (4), and E (5), were isolated from the Okinawan ascidian Didemnidae sp. Their structures were determined by spectroscopic analysis. Biselides A (1), B (2), and C (3) showed cytotoxicity against human cancer cells NCI-H460 and MDA-MB-231.

Original languageEnglish
Pages (from-to)6561-6567
Number of pages7
JournalTetrahedron
Volume61
Issue number27
DOIs
Publication statusPublished - 2005 Jul 4

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Keywords

  • Ascidian
  • Cytotoxicity
  • Macrolide
  • Marine natural product
  • Polyketide

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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