Bioassay-guided fractionation of the cytotoxic constituents of the marine cyanobacterium Lyngbya sp. led to the isolation of biselyngbyaside (1), a new 18-membered macrolide glycoside. The structure of 1 was established by spectroscopic analysis including 2D-NMR techniques and by synthetic studies. Biselyngbyaside (1) exhibits broad-spectrum cytotoxicity in a human tumor cell line panel.
|Number of pages||4|
|Publication status||Published - 2009 Jun 4|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry