Biselyngbyaside, a macrolide glycoside from the marine cyanobacterium lyngbya sp.

Toshiaki Teruya, Hiroaki Sasaki, Kazuhiro Kitamura, Takeshi Nakayama, Kiyotake Suenaga

Research output: Contribution to journalArticlepeer-review

70 Citations (Scopus)

Abstract

Bioassay-guided fractionation of the cytotoxic constituents of the marine cyanobacterium Lyngbya sp. led to the isolation of biselyngbyaside (1), a new 18-membered macrolide glycoside. The structure of 1 was established by spectroscopic analysis including 2D-NMR techniques and by synthetic studies. Biselyngbyaside (1) exhibits broad-spectrum cytotoxicity in a human tumor cell line panel.

Original languageEnglish
Pages (from-to)2421-2424
Number of pages4
JournalOrganic Letters
Volume11
Issue number11
DOIs
Publication statusPublished - 2009 Jun 4

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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