Body mass index associates with disease relapse in patients with giant cell arteritis

Kotaro Matsumoto, Yuko Kaneko, Tsutomu Takeuchi

Research output: Contribution to journalArticle

Abstract

Objective: To identify risk factors associated with disease relapse in giant cell arteritis (GCA). Methods: We reviewed data from 30 consecutive, newly diagnosed patients with GCA. The patients were divided according to relapse or non-relapse status, and their baseline characteristics were compared. Results: Among the 30 patients, 8 relapsed at a median of 28 weeks from GCA diagnosis. Patients with relapse were male-dominant (male: 88% vs female: 41%, P = 0.02) and showed a higher body mass index (BMI, 23 kg/m2 vs 19 kg/m2, P < 0.01) than non-relapse patients. Patients with BMI ≥ 21 kg/m2 showed a significantly higher relapse rate than those with BMI < 21 kg/m2 during the 100-week follow-up (46% vs 0%, log-rank test, P < 0.01). Conclusion: Higher BMI may be associated with relapse in patients with GCA.

Original languageEnglish
JournalInternational Journal of Rheumatic Diseases
DOIs
Publication statusPublished - 2019 Jan 1

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Giant Cell Arteritis
Body Mass Index
Recurrence

Keywords

  • body mass index
  • disease relapse
  • giant cell arteritis
  • vasculitis

ASJC Scopus subject areas

  • Rheumatology

Cite this

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title = "Body mass index associates with disease relapse in patients with giant cell arteritis",
abstract = "Objective: To identify risk factors associated with disease relapse in giant cell arteritis (GCA). Methods: We reviewed data from 30 consecutive, newly diagnosed patients with GCA. The patients were divided according to relapse or non-relapse status, and their baseline characteristics were compared. Results: Among the 30 patients, 8 relapsed at a median of 28 weeks from GCA diagnosis. Patients with relapse were male-dominant (male: 88{\%} vs female: 41{\%}, P = 0.02) and showed a higher body mass index (BMI, 23 kg/m2 vs 19 kg/m2, P < 0.01) than non-relapse patients. Patients with BMI ≥ 21 kg/m2 showed a significantly higher relapse rate than those with BMI < 21 kg/m2 during the 100-week follow-up (46{\%} vs 0{\%}, log-rank test, P < 0.01). Conclusion: Higher BMI may be associated with relapse in patients with GCA.",
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N2 - Objective: To identify risk factors associated with disease relapse in giant cell arteritis (GCA). Methods: We reviewed data from 30 consecutive, newly diagnosed patients with GCA. The patients were divided according to relapse or non-relapse status, and their baseline characteristics were compared. Results: Among the 30 patients, 8 relapsed at a median of 28 weeks from GCA diagnosis. Patients with relapse were male-dominant (male: 88% vs female: 41%, P = 0.02) and showed a higher body mass index (BMI, 23 kg/m2 vs 19 kg/m2, P < 0.01) than non-relapse patients. Patients with BMI ≥ 21 kg/m2 showed a significantly higher relapse rate than those with BMI < 21 kg/m2 during the 100-week follow-up (46% vs 0%, log-rank test, P < 0.01). Conclusion: Higher BMI may be associated with relapse in patients with GCA.

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