Body weight-tailored contrast material injection protocol for 64-detector row computed tomography coronary angiography

Tsuyoshi Isogai, Masahiro Jinzaki, Yutaka Tanami, Hiroyuki Kusuzaki, Minoru Yamada, Sachio Kuribayashi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: The aim of this study was to assess the body weight-tailored contrast material injection protocol for 64-detector computed tomography (CT) to maintain optimal coronary CT attenuation. Materials and methods: A total of 60 patients who underwent CT coronary angiography were assigned to one of three groups: protocol A, total of 0.7 ml kg-1 with 300 mg I/ml iodine concentration; protocol B, total of 0.6 ml kg-1 with 350 mg I/ml; protocol C, total of 0.7 ml kg-1 with 350 mg I/ml. The injection duration was 10 s in all patients. The proportion of intracoronary attenuation values >325 HU was compared on a pervessel and per-patient basis. Results: The attenuation value was significantly more likely to exceed 325 HU with protocol C (95% for reader 1 and 90% for reader 2) than with protocol A or B on the per-vessel analysis (P < 0.05). The attenuation value also signifi cantly exceeded 325 HU with protocol C (95% and 90%, respectively) more often than with protocol A or B on the per-patient analysis (P < 0.05). Conclusion: A total of at least 0.7 ml kg-1 contrast material with 350 mg/ml iodine concentration is required to achieve optimal coronary CT attenuation (>325 HU) with 64-detector CT when using an injection duration of 10 s.

Original languageEnglish
Pages (from-to)33-38
Number of pages6
JournalJapanese Journal of Radiology
Volume29
Issue number1
DOIs
Publication statusPublished - 2011 Jan

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Coronary Angiography
Contrast Media
Tomography
Body Weight
Injections
Iodine
Computed Tomography Angiography

Keywords

  • aphy
  • Cardiac CT
  • Contrast material
  • Injection protocol

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Body weight-tailored contrast material injection protocol for 64-detector row computed tomography coronary angiography. / Isogai, Tsuyoshi; Jinzaki, Masahiro; Tanami, Yutaka; Kusuzaki, Hiroyuki; Yamada, Minoru; Kuribayashi, Sachio.

In: Japanese Journal of Radiology, Vol. 29, No. 1, 01.2011, p. 33-38.

Research output: Contribution to journalArticle

Isogai, Tsuyoshi ; Jinzaki, Masahiro ; Tanami, Yutaka ; Kusuzaki, Hiroyuki ; Yamada, Minoru ; Kuribayashi, Sachio. / Body weight-tailored contrast material injection protocol for 64-detector row computed tomography coronary angiography. In: Japanese Journal of Radiology. 2011 ; Vol. 29, No. 1. pp. 33-38.
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abstract = "Purpose: The aim of this study was to assess the body weight-tailored contrast material injection protocol for 64-detector computed tomography (CT) to maintain optimal coronary CT attenuation. Materials and methods: A total of 60 patients who underwent CT coronary angiography were assigned to one of three groups: protocol A, total of 0.7 ml kg-1 with 300 mg I/ml iodine concentration; protocol B, total of 0.6 ml kg-1 with 350 mg I/ml; protocol C, total of 0.7 ml kg-1 with 350 mg I/ml. The injection duration was 10 s in all patients. The proportion of intracoronary attenuation values >325 HU was compared on a pervessel and per-patient basis. Results: The attenuation value was significantly more likely to exceed 325 HU with protocol C (95{\%} for reader 1 and 90{\%} for reader 2) than with protocol A or B on the per-vessel analysis (P < 0.05). The attenuation value also signifi cantly exceeded 325 HU with protocol C (95{\%} and 90{\%}, respectively) more often than with protocol A or B on the per-patient analysis (P < 0.05). Conclusion: A total of at least 0.7 ml kg-1 contrast material with 350 mg/ml iodine concentration is required to achieve optimal coronary CT attenuation (>325 HU) with 64-detector CT when using an injection duration of 10 s.",
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