TY - JOUR
T1 - Brain-mapping projects using the common marmoset
AU - Okano, Hideyuki
AU - Mitra, Partha
N1 - Funding Information:
This work has been supported by Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS), Ministry of Education, Culture, Sports, Science, and Technology of Japan (MEXT). We would like to thank Dr. Keigo Hikishima for providing unpublished MRI data, Dr. Erika Sasaki, Dr. Atsushi Iriki, Dr. Keigo Hikishima, Dr. Tomomi Shimogori, and Dr. Akira Yoshida for valuable discussions, and Prof. Shigeo Okabe for critical advice for this project.
Funding Information:
The USA and the European Union have adopted different approaches for their brain initiatives. The HBP is a centralized, large-scale enterprise with a computational focus, aimed at building detailed models of neural circuitry, along with a number of complementary sub-projects. In the USA, the Brain Initiative project is more distributed and closer to traditional investigator-driven neuroscience research, with different funding agencies (primarily the National Institute of Health (NIH), National Science Foundation (NSF), Defense Advanced Research Projects Agency (DARPA), Intelligence Advanced Research Projects Activity (IARPA), and private foundations) adopting coordinated yet differentiated strategies. An emphasis on the development of technologies to facilitate neuroscience research forms a basic theme of USA-led initiatives.
Publisher Copyright:
© 2014 The Authors.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Globally, there is an increasing interest in brain-mapping projects, including the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the USA, the Human Brain Project (HBP) in Europe, and the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in Japan. These projects aim to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain. Brain/MINDS is focused on structural and functional mapping of the common marmoset (. Callithrix jacchus) brain. This non-human primate has numerous advantages for brain mapping, including a well-developed frontal cortex and a compact brain size, as well as the availability of transgenic technologies. In the present review article, we discuss strategies for structural and functional mapping of the marmoset brain and the relation of the common marmoset to other animals models.
AB - Globally, there is an increasing interest in brain-mapping projects, including the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the USA, the Human Brain Project (HBP) in Europe, and the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in Japan. These projects aim to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain. Brain/MINDS is focused on structural and functional mapping of the common marmoset (. Callithrix jacchus) brain. This non-human primate has numerous advantages for brain mapping, including a well-developed frontal cortex and a compact brain size, as well as the availability of transgenic technologies. In the present review article, we discuss strategies for structural and functional mapping of the marmoset brain and the relation of the common marmoset to other animals models.
KW - Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS)
KW - Brain-wide connectivity maps
KW - Diffusion tensor imaging (DTI)
KW - Macroscopic structural mapping
KW - Mesoscopic structural mapping
KW - Microscopic structural mapping
UR - http://www.scopus.com/inward/record.url?scp=84927909306&partnerID=8YFLogxK
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U2 - 10.1016/j.neures.2014.08.014
DO - 10.1016/j.neures.2014.08.014
M3 - Review article
C2 - 25264372
AN - SCOPUS:84927909306
VL - 93
SP - 3
EP - 7
JO - Neuroscience Research
JF - Neuroscience Research
SN - 0168-0102
ER -
