Brain stem auditory-evoked potentials in meningomyelocele - Natural history of Chiari II malformations

Toshihiko Nishimura, Koreaki Mori, Yasufumi Uchida, Takayuki Ohira, Kazumi Tamura

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Brain stem auditory-evoked potentials (BAEPs) were recorded in 30 patients with meningomyelocele and shunted hydrocephalus ranging in age from birth to 33 years. Twenty-two of them had Chiari II malformation, one of which was symptomatic. In 22 cases, including 15 with Chiari II malformation, BAEPs were recorded repeatedly after periods ranging from 18 months to 7 years. The results were as follows: (1) III-V interpeak latency (IPL) decreased progressively from prolonged to the normal range with growth until 25 years of age; (2) I-III IPL tended to prolong gradually from the normal range; (3) these findings may indicate that the natural history of Chiari II malformation is delayed maturation of the brain stem and intensification in the elongation and stretching of the hindbrain and lower cranial nerves.

Original languageEnglish
Pages (from-to)316-326
Number of pages11
JournalChild's Nervous System
Issue number6
Publication statusPublished - 1991 Oct 1
Externally publishedYes


  • Brain stem auditory-evoked potentials (BAEPs)
  • Brain-stem function
  • Chiari II malformation
  • Chronological changes
  • Magnetic resonance imaging
  • Meningomyelocele

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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