Brain/MINDS: Brain-mapping project in Japan

Hideyuki Okano, Atsushi Miyawak, Kiyoto Kasai

Research output: Contribution to journalReview articlepeer-review

44 Citations (Scopus)

Abstract

There is an emerging interest in brain-mapping projects in countries across the world, including the USA, Europe, Australia and China. In 2014, Japan started a brain-mapping project called Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS). Brain/MINDS aims to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain, and takes advantage of a unique nonhuman primate animal model, the common marmoset (Callithrix jacchus). In Brain/MINDS, the RIKEN Brain Science Institute acts as a central institute. The objectives of Brain/MINDS can be categorized into the following three major subject areas: (i) structure and functional mapping of a non-human primate brain (the marmoset brain); (ii) development of innovative neurotechnologies for brain mapping; and (iii) human brain mapping; and clinical research. Brain/MINDS researchers are highly motivated to identify the neuronal circuits responsible for the phenotype of neurological and psychiatric disorders, and to understand the development of these devastating disorders through the integration of these three subject areas.

Original languageEnglish
Article number20140310
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume370
Issue number1668
DOIs
Publication statusPublished - 2015 May 19

Keywords

  • Brain mapping by integrated neurotechnologies for disease studies
  • Neuropsychiatric and neurodegenerative diseases
  • Optogenetics
  • Super-resolution microscopy
  • Tissue clearing
  • Transgenic non-human primates

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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