Breast cancer evaluated by contrast harmonic imaging using the pulse inversion method: Report of a case

K. Matsumoto, K. Ohkuma, M. Jinzaki, H. Hiramatsu, S. Kuribayashi, T. Ikeda

Research output: Contribution to journalArticle


A 54-year-old woman was admitted to this institution for further examination and treatment of a mass in the fight breast. The mass was a palpable hard lump that measured approximately 2 cm in diameter. Breast cancer was strongly suspected, and ultrasound examination was performed. The conventional B-mode image showed a well-defined, hypoechoic mass with a lobulated margin in the right mammary gland; the color Doppler image showed a penetrating feeding vessel and intralesional vessels; and the contrast-enhanced color Doppler image showed intense signals from the intralesional vessels. The feeding and intralesional vessels were clearly shown in B-mode contrast harmonic imaging with pulse inversion. It was suggested that B-mode contrast harmonic imaging with pulse inversion is suitable for detection of tumor vessels in a small, superficial organ such as a mammary gland.

Original languageEnglish
Pages (from-to)1427-1430
Number of pages4
JournalJournal of Medical Ultrasonics
Issue number11
Publication statusPublished - 2000 Dec 1



  • Breast cancer
  • Contrast media
  • Harmonic imaging
  • Pulse inversion
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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