Abstract
A new series of high-performance fluorophores named Keio Fluors (KFL), which are based on borondipyrromethene (BODIPY), are reported. The KFL dyes cover a wide spectral range from the yellow (547 nm) to the near-infrared (NIR, 738 nm) region, and their emission wavelength could be easily and subtly controlled based on simple molecular modifications only, without losing their optical properties. This "tailor-made" synthetic strategy for tuning the emission wavelength enabled the creation of fourteen KFL dyes with well-controlled emission colors (yellow, orange, red, far-red, and NIR). Moreover, these KFL dyes also retain their excellent optical properties, such as spectral bands sharper than quantum dots, high extinction coefficients (140000-316000 M-1 cm-1), and high quantum yields (0.56-0.98), without any critical solvent polarity dependent decrease of their brightness. These advantageous characteristics make the KFL dyes potentially useful as new candidates of fluorescent standard dyes to substitute or to complement existing long-wavelength fluorescent dyes, such as cyanines, oxazines, rhodamines, or other BODIPY dyes.
| Original language | English |
|---|---|
| Pages (from-to) | 1096-1106 |
| Number of pages | 11 |
| Journal | Chemistry - A European Journal |
| Volume | 15 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2009 Jan 19 |
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Keywords
- Boron
- Dyes/pigments
- Fluorescent probes
- Imaging agents
ASJC Scopus subject areas
- Chemistry(all)
Cite this
Bright, color-tunable fluorescent dyes in the Vis/NIR region : Establishment of new "tailor-made" multicolor fluorophores based on borondipyrromethene. / Umezawa, Keitaro; Matsui, Akihiro; Nakamura, Yuki; Citterio, Daniel; Suzuki, Koji.
In: Chemistry - A European Journal, Vol. 15, No. 5, 19.01.2009, p. 1096-1106.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bright, color-tunable fluorescent dyes in the Vis/NIR region
T2 - Establishment of new "tailor-made" multicolor fluorophores based on borondipyrromethene
AU - Umezawa, Keitaro
AU - Matsui, Akihiro
AU - Nakamura, Yuki
AU - Citterio, Daniel
AU - Suzuki, Koji
PY - 2009/1/19
Y1 - 2009/1/19
N2 - A new series of high-performance fluorophores named Keio Fluors (KFL), which are based on borondipyrromethene (BODIPY), are reported. The KFL dyes cover a wide spectral range from the yellow (547 nm) to the near-infrared (NIR, 738 nm) region, and their emission wavelength could be easily and subtly controlled based on simple molecular modifications only, without losing their optical properties. This "tailor-made" synthetic strategy for tuning the emission wavelength enabled the creation of fourteen KFL dyes with well-controlled emission colors (yellow, orange, red, far-red, and NIR). Moreover, these KFL dyes also retain their excellent optical properties, such as spectral bands sharper than quantum dots, high extinction coefficients (140000-316000 M-1 cm-1), and high quantum yields (0.56-0.98), without any critical solvent polarity dependent decrease of their brightness. These advantageous characteristics make the KFL dyes potentially useful as new candidates of fluorescent standard dyes to substitute or to complement existing long-wavelength fluorescent dyes, such as cyanines, oxazines, rhodamines, or other BODIPY dyes.
AB - A new series of high-performance fluorophores named Keio Fluors (KFL), which are based on borondipyrromethene (BODIPY), are reported. The KFL dyes cover a wide spectral range from the yellow (547 nm) to the near-infrared (NIR, 738 nm) region, and their emission wavelength could be easily and subtly controlled based on simple molecular modifications only, without losing their optical properties. This "tailor-made" synthetic strategy for tuning the emission wavelength enabled the creation of fourteen KFL dyes with well-controlled emission colors (yellow, orange, red, far-red, and NIR). Moreover, these KFL dyes also retain their excellent optical properties, such as spectral bands sharper than quantum dots, high extinction coefficients (140000-316000 M-1 cm-1), and high quantum yields (0.56-0.98), without any critical solvent polarity dependent decrease of their brightness. These advantageous characteristics make the KFL dyes potentially useful as new candidates of fluorescent standard dyes to substitute or to complement existing long-wavelength fluorescent dyes, such as cyanines, oxazines, rhodamines, or other BODIPY dyes.
KW - Boron
KW - Dyes/pigments
KW - Fluorescent probes
KW - Imaging agents
UR - http://www.scopus.com/inward/record.url?scp=58449087255&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58449087255&partnerID=8YFLogxK
U2 - 10.1002/chem.200801906
DO - 10.1002/chem.200801906
M3 - Article
C2 - 19117043
AN - SCOPUS:58449087255
VL - 15
SP - 1096
EP - 1106
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
IS - 5
ER -