Abstract
A case of Burkitt's lymphoma with granulocytosis including immature cells and a high level of C-reactive protein (CRP) is reported. The activity of interleukin-1 alpha (IL-1 alpha) was detected in the sera, although its activity was not detected in the supernate of the cultured lymphoblasts. The lymphoblasts stimulated production of IL-1 alpha from human umbilical endothelial cells. Therefore, the lymphoblasts infiltrating bone marrow may have stimulated production of IL-1 alpha from bone marrow stroma cells, and IL-1 alpha may have induced granulocytosis and a high level of CRP.
| Original language | English |
|---|---|
| Pages (from-to) | 542-544 |
| Number of pages | 3 |
| Journal | [Rinshō ketsueki] The Japanese journal of clinical hematology |
| Volume | 33 |
| Issue number | 4 |
| Publication status | Published - 1992 Apr |
ASJC Scopus subject areas
- Medicine(all)